Properties, mode of insecticidal action, environmental exposure pathways, and uses of the insecticide sulfoxaflor; sulfoxaflor environmental science review part I
Bibliographic record
Abstract
Sulfoxaflor (SFX, CAS# 946578-00-3) is marketed by Corteva Agrisciences Inc. as Isoclast®. SFX is a Group 4C, nicotinic acetylcholine receptor agonist and is a systemic insecticide that is most active against sucking insects. This paper critically reviews and characterizes the physical and chemical properties of SFX to facilitate development of conceptual models that identify environmental compartments with the greatest potential concentrations and organisms most likely to be exposed. These conceptual models were assessed in a Weight of Evidence (WoE) framework to identify scenarios and organisms at greatest risk. The solubility of SFX in water is approximately 550 mg L− 1 and the POW of 0.8, so it will not bioconcentrate or undergo trophic transfer. It has the potential to move in soils, but this is unlikely because of the short half-life (hours to 2–5 days) in agricultural soils where bacteria mediate dissipation. Some of the transformation products of SFX have longer half-lives (months) in soil and are more mobile but are less toxic and not a concern for adverse effects. SFX does not undergo significant photolysis or hydrolysis in water, but this does not lead to a risk in aquatic systems because it is not approved for over-water use and the label recommends buffer zones to protect sensitive aquatic areas. Overall, use of SFX under good agricultural practices is unlikely to result in biologically relevant exposures in non-target species or areas in the environment.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.002 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.002 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.004 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".