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Record W4408976572 · doi:10.1093/jhps/hnaf011.280

EP5.18 Clinical Characteristics and CT Morphology Predict Earlier Onset of Femoroacetabular Impingement Symptoms

2025· article· en· W4408976572 on OpenAlexaff
Sasha Carsen, Kyle P. O’Connor, Étienne L. Belzile, Stephanie W. Mayer, Bruce A. Levy, Jeffrey J. Nepple

Bibliographic record

VenueJournal of Hip Preservation Surgery · 2025
Typearticle
Languageen
FieldMedicine
TopicHip disorders and treatments
Canadian institutionsUniversité LavalChildren's Hospital of Eastern Ontario
Fundersnot available
KeywordsFemoroacetabular impingementMedicineMorphology (biology)RadiologyGeology

Abstract

fetched live from OpenAlex

Abstract Introduction: The onset of hip pain due to symptomatic femoroacetabular impingement (FAI) is highly variable, with some patients presenting in adolescence while others begin to experience pain in middle age. Factors driving the development of symptoms in FAI remain poorly understood. The purpose of the current study was to identify patient factors and CT hip morphology parameters associated with time of onset of FAI symptoms in a large, multicenter prospective study. Methods: This is a prospective, multicenter study of symptomatic FAI. Inclusion criteria were patients aged 14-45 treated with primary hip arthroscopy. Exclusion criteria was FAI with associated diseases or advanced osteoarthritis (Tonnis 2+). Age of symptom onset by patient self-report. Clinical characteristics and low-dose CT data was analyzed for associations using uni- and multi-variable analysis. Results were reported as unstandardized beta estimates (uβ). P-values ≤0.05 were significant. Kaplan-Meier (KM) estimates determined cumulative FAI symptom development by age. Results: The study cohort included 679 patients. Mean age was 24.9±7.8 years and 56% females. Mean age of symptom onset was 22.8±7.6 years. In univariate analysis, earlier onset of symptoms was noted in females (22.3 versus 23.5 years, p=0.02), BMI <30 kg/m2 (22.4 versus 24.9 years, p<0.001), sports participation (21.0 versus 25.7 years, p<0.001), alpha angles at 2:00 <63° (21.9 versus 24.0 years, p<0.001), coverage at 2:00 <55% (22.3 versus 24.4 years, p=0.01), and acetabular version <0° (21.4 versus 23.5 years, p<0.001). Multivariable predictors of earlier onset were sports participation (uβ: -4.194, p<0.001), lower acetabular version (uβ: 0.240, p<0.001), lower BMI (uβ: 0.264, p<0.001), less coverage at 2:00(uβ: 0.295, p<0.001), being female (uβ: 1.414, p=0.027), and smaller alpha angles at 2:00 (uβ: 0.056, p=0.041). KM analysis demonstrated cumulative prevalence of symptomatic FAI at the age of 15-, 20-, 25-, 30-, and 35-years of 17%, 47%, 64%, 79%, and 93%, respectively. Conclusion: A variety of factors predict earlier age of onset of FAI symptoms, with many factors potentially associated with more instability features (female sex, lower alpha angle, less acetabular coverage) than impingement features (less acetabular version). Further research is needed to better define the pathophysiology of FAI, including potential role of instability.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.019
Threshold uncertainty score0.385

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.351
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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