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Record W4408980555 · doi:10.21037/map-25-ab123

AB123. SOH25_AB_365. Quantitative analysis of indocyanine green fluorescence angiography in colorectal surgery: a systematic review of the literature

2025· review· en· W4408980555 on OpenAlexaboutno aff
Philip D. McEntee, Ashokkumar Singaravelu, Cathleen McCarrick, E. Murphy, Patrick A. Boland, Ronan A. Cahill

Bibliographic record

VenueMesentery and Peritoneum · 2025
Typereview
Languageen
FieldMedicine
TopicCardiac, Anesthesia and Surgical Outcomes
Canadian institutionsnot available
Fundersnot available
KeywordsIndocyanine greenMedicineIndocyanine green angiographySystematic reviewRadiologySurgeryMEDLINEChemistryFluorescein angiographyBiochemistry

Abstract

fetched live from OpenAlex

Background: Indocyanine green fluorescence angiography (ICGFA) during colorectal surgery is associated with reduced rates of post-operative anastomotic complications. Because interpretation of ICGFA is subjective, quantification has been proposed to address inter-user variability. This study reviews the published literature regarding ICGFA quantification during colorectal surgery with a focus on clinical deployment. Methods: A systematic review of English language publications was performed in PubMed, Scopus, Web of Science and Cochrane Library on 29th August 2024, updated to 18th November 2024 following PRISMA guidelines. All clinical studies referencing ICGFA quantification during colorectal surgery were included with the Newcastle Ottawa scale used to assess quality. Results: A total of 1,428 studies were screened, resulting in the selection of 22 studies (1,469 patients). Significant heterogeneity of ICGFA methodology, quantification methods, and parameter selection was noted with only three being scored “high” quality. Four studies (154 patients) conducted real-time analyses of the fluorescence signal (others were post-hoc analyses) and four utilised artificial intelligence methods. Eleven studies only included patients undergoing left-sided resection, with six of these focusing specifically on rectal resections. Only one study employed the quantification method to guide intra-operative decision-making regarding transection of the colonic segment. Twenty-six different perfusion parameters were assessed, with time from injection to visible fluorescence and maximum intensity the most commonly (but not only) correlated parameters regarding anastomotic complication. Conclusions: Quantification of the ICGFA signal for colorectal surgery is feasible but has so far seen limited academic advancement beyond feasibility.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.025
Threshold uncertainty score0.904

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0090.006
Bibliometrics0.0010.005
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.316
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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