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Complex decision-making of people's use of opioid agonist therapy during pregnancy: Troubling the concept of ‘non-compliance’

2025· article· en· W4408989583 on OpenAlexafffund
Rose A. Schmidt, Amaya Perez‐Brumer, Nat Kaminski, Ashley Smoke, Akosua Gyan-Mante, Ningwakwe George, Tara Gomes, Brian Rush, Carol Strıke

Bibliographic record

VenueSocial Science & Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicPrenatal Substance Exposure Effects
Canadian institutionsSt. Michael's HospitalPublic Health OntarioUniversity of TorontoCentre for Addiction and Mental Health
FundersSocial Sciences and Humanities Research Council of Canada
KeywordsCompliance (psychology)PregnancyMedicineOpioidPsychotherapistPsychologyPsychiatrySocial psychologyInternal medicine

Abstract

fetched live from OpenAlex

Clinical guidelines strongly recommend that pregnant people with opioid use disorder be offered Opioid Agonist Therapy (OAT); however, access to and retention in substance use services are influenced by a multitude of factors. We conducted 25 semi-structured qualitative interviews with pregnant and recently pregnant people who used opioids or OAT before their pregnancy. Participants were recruited from various health and social services, through social media and by word of mouth. For analysis, we used a voice-centred relational method; each transcript was read four times looking for different levels of influence in participants' stories (i.e., individual, interpersonal, societal). The participant's narratives highlighted how they navigated the expectations of 'good patient' and 'good mother.' We identified four trajectories of OAT use during pregnancy: two that represent 'compliance' and two that represent 'non-compliance.' While compliant patients used OAT out of concern for the health of their fetus and because it was medically recommended, the decision to not use OAT occurred in the context of weighing multiple, not only medical risks. Based on past experiences navigating health and social services, some participants made potentially medically risky decisions to avoid negative interactions with health and social care. Our results underscore that health and social service delivery is shaped by paternalistic measures aimed at controlling the behaviour of pregnant people who use drugs and reinforce the need for alternative approaches beyond control to foster more inclusive, supportive, and empathetic support for women who use drugs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.028
metaresearch head score (Gemma)0.042
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.028
Threshold uncertainty score0.148

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0280.042
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0150.037
Scholarly communication0.0080.009
Open science0.0020.009
Research integrity0.0040.008
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.353
Teacher spread0.311 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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