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Record W4408997124 · doi:10.1016/j.cattod.2025.115286

Sn-silica catalyzes cheese whey to lactic acid in a fluidized bed reactor

2025· article· en· W4408997124 on OpenAlexafffund
P.A. Rivera-Quintero, M. Olga Guerrero‐Pérez, Enrique Rodrı́guez-Castellón, Gregory S. Patience

Bibliographic record

VenueCatalysis Today · 2025
Typearticle
Languageen
FieldEngineering
TopicCatalysis for Biomass Conversion
Canadian institutionsPolytechnique Montréal
FundersEuropean Regional Development FundNational Research Council CanadaNatural Sciences and Engineering Research Council of CanadaMinisterio de Ciencia e InnovaciónUniversidad de Málaga
KeywordsFluidized bedLactic acidChemistryCatalysisHeterogeneous catalysisChemical engineeringOrganic chemistryChromatographyBacteriaBiology

Abstract

fetched live from OpenAlex

Worldwide, the dairy industry produces 200 million tons per year of whey. Among the most abundant components of cheese whey is lactose, a low-priced raw material for nutraceuticals, animal feed, and high value products such as lactic acid (LA)., a specialty chemical platform in the pharmaceutical, cosmetic, and in the food industry, and is the precursor to polylactic acid, a biodegradable polymer. Here, we propose a fluidized bed process that atomizes an aqueous lactose solution directly into a catalytic bed operating at 325 ∘ C to produce LA. We synthesized silica supported Sn catalysts by varying the metal loading (from 0 to 0.1 g g −1 of Sn) and analyzed its physicochemical properties. This research highlights the critical role of Sn as an active site to hydrolyse/isomerize/retro-aldol/dehydrate/crack lactose to lactic acid in a gas phase environment. All catalysts achieved complete conversion. SiO 2 impregnated with 0.1 g g −1 Sn catalyst achieved the maximum lactic acid yield of 23 % at 2 h of the reaction. Lactic acid yield declined thereafter due to coke blocking the active catalytic sites. XPS, Raman and CHN analysis highlighted changes in carbon distribution and evidence of coke accumulation in the spent catalyst. This article brings new findings related to significant challenges related to the continuous operation of a fluidized bed reactor in the conversion of lactose and strategies to mitigate agglomeration and coke formation. • A two fluid nozzle atomizes lactose solution into a fluidized bed of Sn-SiO 2 • Sn-silica supported catalysts convert lactose to lactic acid at 23 % yield at 2 h. • Lactic acid yield rises with Sn loading up to 0.1 g g −1 , with full lactose conversion. • Coke deactivates catalyst after 3 h operation confirmed by Raman spectroscopy and XPS.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.015
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.003
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.219
Teacher spread0.214 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes2
Has abstractyes

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