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Record W4409057418 · doi:10.30699/mmlj17.6.2.39

Relationship between Liver Function Tests Levels with Degree of FibroScan Test in non-alcoholic Fatty Liver Disease

2023· article· en· W4409057418 on OpenAlexvenueno aff
Hassan Neishaboori, Ali akbar Choubchian, Fereshteh Tamimi

Bibliographic record

VenueModern Medical Laboratory Journal · 2023
Typearticle
Languageen
FieldMedicine
TopicLiver Disease Diagnosis and Treatment
Canadian institutionsnot available
FundersUniversity of ZanjanZanjan University of Medical Sciences
KeywordsFatty liverInternal medicineAlcoholic liver diseaseGastroenterologyLiver function testsBreath testMedicineDiseaseDegree (music)CirrhosisPhysics

Abstract

fetched live from OpenAlex

Background and Objectives: Non-Alcoholic Fatty Liver Disease (NAFLD) occurs when liver fat content exceeds 5-10%.The initial stage is simple fatty liver, which can progress to alcoholic steatohepatitis and ultimately lead to cirrhosis of the liver.The first step in treatment is a weight loss diet.Methods: In this study, patients with non-alcoholic fatty liver disease who had undergone all necessary tests to rule out other causes of liver involvement, such as viral and autoimmune hepatitis and Wilson's disease, were evaluated.These patients were approved by a gastroenterologist and underwent a FibroScan over a six-month period to assess their condition.The initial checklist included demographic information (height and weight), blood pressure, history of alcohol consumption, and liver enzyme levels.Results: Among 86 participants, 25 (29.1%) had Grade 0 fatty liver, 39 (54.7%) had Grade 1, 14 (11.6%) had Grade 2, and 8 (4.7%) had Grade 3 fatty liver.Additionally, 8 patients had anemia, 3 (2.5%) had elevated bilirubin levels, 3 (2.5%) had iron deficiency, and only 1 patient had liver issues related to an autoimmune problem or specific disease.There was no significant relationship between the FibroScan score and enzyme levels in any gender. Conclusion:The prevalence of non-alcoholic fatty liver disease is higher in women than in men, and liver enzymes do not accurately reflect the degree of liver fibrosis.It is recommended that imaging methods, especially FibroScan, be used instead of routine enzyme level measurements to assess liver tissue conditions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.064
GPT teacher head0.302
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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