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Record W4409128606 · doi:10.4103/jcrt.jcrt_1419_23

Lumbosacral plexopathy after short-course neoadjuvant radiotherapy for rectal cancer: A case report

2024· article· en· W4409128606 on OpenAlexaff
Febin Antony, Davyd R. Hooper, James Koenig, Maged N. F. Nashed

Bibliographic record

VenueJournal of Cancer Research and Therapeutics · 2024
Typearticle
Languageen
FieldMedicine
TopicColorectal and Anal Carcinomas
Canadian institutionsUniversity of ManitobaCancerCare Manitoba
Fundersnot available
KeywordsMedicineLumbosacral plexusRadiation therapyLumbosacral jointSurgeryColorectal cancerComplicationMagnetic resonance imagingRadiologyCancerInternal medicine

Abstract

fetched live from OpenAlex

ABSTRACT: Radiation-induced lumbosacral plexopathy (RILSP) is a rare complication associated with pelvic radiotherapy. Literature is scant about the incidence of RILSP after a neoadjuvant short-course radiotherapy (RT) in rectal cancer. In this report, we detail the symptoms, signs, and management of RILSP. Volumetric modulated arc therapy was used for delivering preoperative short-course RT in our rectal cancer patient. Six months after the completion of RT, the patient presented with symptoms of lower extremity motor and sensory impairment. An electrodiagnostic study revealed a pattern of bilateral sciatic nerve injury or a lower lumbosacral plexus abnormality. Magnetic resonance imaging showed radiation-related edema in the region of the lumbosacral plexus. Further blood and serum investigations ruled out other inflammatory and infectious differential diagnoses, thus a diagnosis of RILSP was made. He was initiated on analgesics and was also referred to physiotherapy and rehabilitation. After 2 months, his symptoms stabilized.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.718
Threshold uncertainty score0.443

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.087
GPT teacher head0.458
Teacher spread0.371 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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