MétaCan
Menu
Back to cohort
Record W4409148791 · doi:10.1038/s41588-025-02127-z

Psychiatric genetics in the diverse landscape of Latin American populations

2025· review· en· W4409148791 on OpenAlexaff
Estela M. Bruxel, Diego Luiz Rovaris, Síntia Belangero, Gabriela Chavarría‐Soley, Alfredo B. Cuéllar‐Barboza, José Jaime Martínez‐Magaña, Sheila T. Nagamatsu, Caroline M. Nievergelt, Diana L. Núñez-Ríos, Vanessa Ota, Roseann E. Peterson, Laura Sloofman, Amy M. Adams, Elinette Albino, Ángel T. Alvarado, Diego Andrade-Brito, Paola Arguello-Pascualli, Cibele Edom Bandeira, Claiton H.D. Bau, Cynthia M. Bulik, Joseph D. Buxbaum, Carolina Cappi, Nadia Saraí Corral-Frías, Alejo Corrales, Fabiana Corsi‐Zuelli, James J. Crowley, Renata B. Cupertino, Bruna Santos da Silva, Simoneide Souza Titze de Almeida, Juan De La Hoz, Diego A. Forero, Gabriel R. Fries, Joel Gelernter, Yeimy González‐Giraldo, Eugênio H. Grevet, Dorothy E. Grice, Adriana Hernández-Garayua, John M. Hettema, Agustín Ibáñez, Iuliana Ionita‐Laza, María Claudia Lattig, Yago Carvalho Lima, Yi-Sian Lin, Sandra López‐León, Camila Marcelino Loureiro, Verónica Martínez-Cerdeño, Gabriela Ariadna Martínez-Levy, Kyle Melín, Daniel Moreno‐De‐Luca, Carolina Muniz Carvalho, Ana Maria Olivares, Victor Fernandes de Oliveira, Rafaella Ormond, Abraham A. Palmer, Alana Castro Panzenhagen, Maria Rita Passos‐Bueno, Qian Peng, Eduardo Pérez‐Palma, Miguel L. Prieto, Panos Roussos, Sandra Sanchez‐Roige, Hernando Santamaría‐García, Flávio Shansis, Rachel R. Sharp, Eric A. Storch, Maria Eduarda Araujo Tavares, Grace E. Tietz, Bianca A. Torres-Hernández, Luciana Tovo‐Rodrigues, M. Pilar Trelles, Eva Trujillo, María Marcela Velásquez Toledo, Fernando Vera-Urbina, Georgios Voloudakis, Talía Wegman-Ostrosky, Jenny Zhen‐Duan, Hang Zhou, Marcos Santoro, Elizabeth G. Atkinson, Paola Giusti‐Rodríguez, Janitza L. Montalvo‐Ortiz

Bibliographic record

VenueNature Genetics · 2025
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic Associations and Epidemiology
Canadian institutionsChild, Adolescent and Family Mental HealthAlberta Health ServicesUniversity of British Columbia
FundersNational Human Genome Research InstituteNational Institute on Drug AbuseNational Institute on AgingU.S. Department of Health and Human ServicesVetenskapsrådetNational Institute of Mental Health
KeywordsPsychiatric geneticsGenome-wide association studyLatin AmericansGenomicsGenetic associationBiologyPsychiatryEvolutionary biologyGeneticsMedicineGenomeSchizophrenia (object-oriented programming)Single-nucleotide polymorphismPolitical scienceGenotypeGene

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.007
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0020.003
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.347
Teacher spread0.321 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations17
Published2025
Admission routes1
Has abstractno

Explore more

Same venueNature GeneticsSame topicGenetic Associations and EpidemiologyFrench-language works237,207