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Record W4409157115 · doi:10.1126/sciadv.ads4593

FairDiffusion: Enhancing equity in latent diffusion models via fair Bayesian perturbation

2025· article· en· W4409157115 on OpenAlexaff
Yan Luo, Muhammad Osama Khan, Congcong Wen, Muhammad Muneeb Afzal, Titus Fidelis Wuermeling, Min Shi, Yu Tian, Yi Fang, Mengyu Wang

Bibliographic record

VenueScience Advances · 2025
Typearticle
Languageen
FieldComputer Science
TopicAI in cancer detection
Canadian institutionsArtificial Intelligence in Medicine (Canada)
FundersNational Eye Institute
KeywordsGenerative grammarComputer scienceEquity (law)Generative modelHealth equityBayesian probabilityMachine learningModalitiesArtificial intelligenceHealth careData sciencePolitical scienceSociology

Abstract

fetched live from OpenAlex

Recent advancements in generative AI, particularly diffusion models, have proven valuable for text-to-image synthesis. In health care, these models offer immense potential in generating synthetic datasets and aiding medical training. Despite these strong performances, it remains uncertain whether the image generation quality is consistent across different demographic subgroups. To address this, we conduct a comprehensive analysis of fairness in medical text-to-image diffusion models. Evaluations of the Stable Diffusion model reveal substantial disparities across gender, race, and ethnicity. To reduce these biases, we propose FairDiffusion, an equity-aware latent diffusion model that improves both image quality and the semantic alignment of clinical features. In addition, we design and curate FairGenMed, a dataset tailored for fairness studies in medical generative models. FairDiffusion is further assessed on HAM10000 (dermatoscopic images) and CheXpert (chest x-rays), demonstrating its effectiveness in diverse medical imaging modalities. Together, FairDiffusion and FairGenMed advance research in fair generative learning, promoting equitable benefits of generative AI in health care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.024
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.006
Threshold uncertainty score0.033

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.024
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0020.003
Open science0.0020.004
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.304
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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