Residue of allocryptopine and protopine in tissues and eggs of laying hens using ultra-high performance liquid chromatography–tandem mass spectrometry
Bibliographic record
Abstract
The residues of allocryptopine (ALL) and protopine (PRO) in the eggs and tissues of laying hens from the veterinary drug Bopp Total Alkali Powder® were evaluated. UPLC-MS/MS technology was used to accurately determine these components. The study found that at a dose of 400 mg/kg, PRO in eggs reached a peak of 2.8 µg/kg on the seventh day of administration and was undetectable five days after stopping the medication. ALL was not detected throughout the study. At a dose of 2000 mg/kg, one day after stopping the medication, the residues of PRO and ALL reached 16.72 µg/kg and 8.61 µg/kg, respectively. Seven days after stopping the medication, PRO was undetectable, but there was still a residue of ALL. Tissue samples showed that two hours after stopping the medication, the concentrations of both components significantly increased in all tissues but rapidly declined within 24 h. Seven days after stopping the medication, no residues were detected in all tissues. The study suggests that the risk of residue is low when using Bopp Total Alkali Powder® at a dose of 400 mg/kg. However, using a dose of 2000 mg/kg may increase the risk of residue, so it is recommended to stop the medication for at least seven days to ensure food safety.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.002 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".