MétaCan
Menu
Back to cohort
Record W4409217711 · doi:10.1016/j.clnu.2025.03.018

The GLIM consensus approach to diagnosis of malnutrition: A 5-year update

2025· article· en· W4409217711 on OpenAlexaff
Tommy Cederholm, Gordon L. Jensen, María Isabel Toulson Davisson Correia, Marı́a Cristina González, Ryoji Fukushima, Veeradej Pisprasert, Renée Blaauw, Diana Cárdenas, Fernando Carrasco, Alfonso J. Cruz‐Jentoft, Cristina Cuerda, David C. Evans, Vanessa Fuchs‐Tarlovsky, Leah Gramlich, Hanping Shi, Jeanette M. Hasse, M. Hiesmayr, Naoki Hiki, Harriët Jager‐Wittenaar, Mohammad Shukri Jahit, Anayanet Jáquez, Heather Keller, Stanisław Kłęk, Ainsley Malone, Kris M. Mogensen, Naoharu Mori, Manpreet S. Mundi, Maurizio Muscaritoli, Doris Hui Lan Ng, Ibolya Nyulasi, Matthias Pirlich, S. Schneider, M.A.E. de van der Schueren, S. Siltharm, Pierre Singer, Alison Steiber, Kelly A. Tappenden, Jianchun Yu, A. Van Gossum, Jaw‐Yuan Wang, Marion F. Winkler, Rocco Barazzoni, Charlene Compher

Bibliographic record

VenueClinical Nutrition · 2025
Typearticle
Languageen
FieldMedicine
TopicNutrition and Health in Aging
Canadian institutionsResearch Institute for AgingUniversity of Alberta
Fundersnot available
KeywordsMedicineMalnutritionIntensive care medicinePediatricsInternal medicine

Abstract

fetched live from OpenAlex

BACKGROUND: The Global Leadership Initiative on Malnutrition (GLIM) introduced an approach for malnutrition diagnosis in 2019 comprised of screening followed by assessment of three phenotypic criteria: weight loss, low BMI, and low muscle mass, and two etiologic criteria: reduced food intake/assimilation, and inflammation/disease burden. This planned update reconsiders the GLIM framework based on published knowledge and experience over the past five years. METHODS: A GLIM working group (n = 43 members) conducted a literature search spanning 2019-2024 using the keywords "Global Leadership Initiative on Malnutrition or GLIM". Prior GLIM activities providing guidance for use of the criteria on muscle mass and inflammation were reviewed. Successive rounds of review and revision were used to achieve consensus. RESULTS: More than 400 scientific reports are published in peer-reviewed journals, forming the basis of 10 systematic reviews, some including meta-analyses of GLIM validity that indicate strong construct and predictive validity. Limitations and future priorities are discussed. Working group findings suggest that assessment of low muscle mass should be guided by experience and available technological resources. Clinical judgement may suffice to evaluate the inflammation/disease burden etiologic criterion. No revisions of the weight loss, low BMI, or reduced food intake/assimilation criteria are suggested. Following two rounds of review and revision, the working group secured 100 % agreement with the conclusions reported in the 5-year update. CONCLUSION: Ongoing initiatives target priorities that include malnutrition risk screening procedures, GLIM adaptation to the intensive care setting, assessment in support of the reduced food intake/assimilation criterion, and determination of malnutrition in obesity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.494
Threshold uncertainty score0.353

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.082
GPT teacher head0.434
Teacher spread0.352 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations48
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueClinical NutritionSame topicNutrition and Health in AgingFrench-language works237,207