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Record W4409234700 · doi:10.1212/wnl.0000000000209072

Non-invasive Classification of Myasthenia Gravis and Other Ocular Disorders Using Electrooculogram Features (P1-11.008)

2025· article· en· W4409234700 on OpenAlexaff
Hans Katzberg, Todd Le, Mona Irannejad, Sarah Berger, Arun Sundaram, Karl Magtibay, Lahiru Fernando, Sridhar Krishnan, Kevin E. Thorpe, Brian J. Murray, Karthi Umapathi, Mark I. Boulos

Bibliographic record

VenueNeurology · 2025
Typearticle
Languageen
FieldMedicine
TopicMyasthenia Gravis and Thymoma
Canadian institutionsSunnybrook Health Science CentreHealth Sciences CentreUniversity Health NetworkToronto Metropolitan UniversityUniversity of Toronto
Fundersnot available
KeywordsMyasthenia gravisMedicineOcular myastheniaDermatologyInternal medicine

Abstract

fetched live from OpenAlex

(1) To use electrooculogram (EOG) to differentiate patients with Myasthenia Gravis (MG) from those with extra-ocular movement abnormalities due to other etiologies (non-MG group). (2) To test the sensitivity of EOG features to classifying the EOG data into Controls (free of extra-ocular abnormalities), MG patients, and a non-MG group.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.272
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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