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Record W4409260640 · doi:10.1101/2025.04.07.644581

The genome sequence of the hemlock woolly adelgid, <i>Adelges tsugae</i> Annand 1924

2025· preprint· en· W4409260640 on OpenAlexafffund
Bryan M. T. Brunet, Dustin T Dial, Gaelen R. Burke, Carol D. von Dohlen, Julia Douglas Freitas, Haley Sanderson, Afiya Razia Chida, Samantha Jones, Fergal J. Martin, Leanne Haggerty, Stephen W. Scherer, Jiannis Ragoussis, Steven J.M. Jones, Robert G. Foottit, Nathan P. Havill

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicViral Infectious Diseases and Gene Expression in Insects
Canadian institutionsMcGill Genome CentreSickKids FoundationUniversity of TorontoAgriculture and Agri-Food CanadaUniversity of British ColumbiaHospital for Sick ChildrenCanada's Michael Smith Genome Sciences Centre
FundersAgriculture and Agri-Food CanadaHospital for Sick ChildrenUniversity of Toronto
KeywordsBiologyWhole genome sequencingZoologySequence (biology)VirologyGenomeGeneticsGene

Abstract

fetched live from OpenAlex

Abstract The genome of the hemlock woolly adelgid ( Adelges tsugae ) is presented in 10 chromosomal pseudomolecules along with 132 unplaced scaffolds for a combined length of 216.56 Mb. The genome is highly contiguous, with a benchmarking universal single-copy orthologs (BUSCO) completion score of 98.25%, an N50 of 20.54 Mb, and the longest scaffold 37.41 Mb in length. On the basis of chromosomal synteny with other aphid genomes, the hemlock woolly adelgid’s genome is composed of 8 autosomes and two sex (X) chromosomes. Annotation of the assembly identified 11,800 coding genes, 1,930 non-coding genes, and 20,403 mRNA transcripts. The mitogenome is also presented in a single, annotated, circular contig 25,980 bases in length. Species taxonomy Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Aphidomorpha; Adelgoidea; Adelgidae; Adelges ; Annandina ; Adelges ( Annandina ) tsugae Annand, 1924 (NCBI:txid357502)

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.018

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.232
Teacher spread0.222 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

Explore more

Same venuebioRxiv (Cold Spring Harbor Laboratory)Same topicViral Infectious Diseases and Gene Expression in InsectsFrench-language works237,207