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Record W4409278937 · doi:10.1089/neu.2024.0301

Linking Symptom Inventories Using Semantic Textual Similarity

2025· article· en· W4409278937 on OpenAlexaff
Eamonn Kennedy, Shashank Vadlamani, Hannah M. Lindsey, Kelly Peterson, Kristen Dams-O’Connor, Ronak Agarwal, Houshang Amiri, Talin Babikian, David Baron, Erin D. Bigler, Karen Caeyenberghs, Lisa Delano‐Wood, Seth G. Disner, Ekaterina Dobryakova, Blessen C. Eapen, Rachel M. Edelstein, Carrie Esopenko, Helen M. Genova, Elbert Geuze, Naomi J. Goodrich‐Hunsaker, Jordan Grafman, Asta K. Håberg, Cooper B. Hodges, Kristen R. Hoskinson, Elizabeth S Hovenden, Andrei Irimia, Neda Jahanshad, Ruchira M. Jha, Finian Keleher, Kimbra Kenney, Inga K. Koerte, Spencer W. Liebel, Abigail Livny, Marianne Løvstad, Sarah L. Martindale, Jeffrey E. Max, Andrew R. Mayer, Timothy B. Meier, Deleene S. Menefee, Abdalla Z. Mohamed, Stefania Mondello, Martin M. Monti, Rajendra A. Morey, Virginia Newcombe, Mary R. Newsome, Alexander Olsen, Nicholas J. Pastorek, Mary Jo Pugh, Adeel Razi, Jacob E. Resch, Jared A. Rowland, Kelly Russell, Nicholas P. Ryan, Randall S. Scheibel, Adam Schmidt, Gershon Spitz, Jaclyn A. Stephens, Assaf Tal, Leah D. Talbert, Maria Carmela Tartaglia, Brian Taylor, Sophia I. Thomopoulos, Maya Troyanskaya, Eve M. Valera, Harm J. van der Horn, John D. Van Horn, Ragini Verma, Benjamin Wade, William C. Walker, Ashley L. Ware, J. Kent Werner, Keith Owen Yeates, Ross Zafonte, Michael Zeineh, Brandon A. Zielinski, Paul M. Thompson, Frank G. Hillary, David F. Tate, Elisabeth A. Wilde, Emily L. Dennis

Bibliographic record

VenueJournal of Neurotrauma · 2025
Typearticle
Languageen
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsAlberta Children's HospitalUniversity Health NetworkUniversity of TorontoUniversity of ManitobaOccupational Cancer Research CentreChildren's Hospital Research Institute of ManitobaCanadian Institute for Advanced Research
FundersNational Institute of Neurological Disorders and StrokeU.S. Department of Veterans Affairs
KeywordsSimilarity (geometry)Semantic similarityNatural language processingPsychologyInformation retrievalComputer scienceArtificial intelligence

Abstract

fetched live from OpenAlex

An extensive library of symptom inventories has been developed over time to measure clinical symptoms of traumatic brain injury (TBI), but this variety has led to several long-standing issues. Most notably, results drawn from different settings and studies are not comparable. This creates a fundamental problem in TBI diagnostics and outcome prediction, namely that it is not possible to equate results drawn from distinct tools and symptom inventories. Here, we present an approach using semantic textual similarity (STS) to link symptoms and scores across previously incongruous symptom inventories by ranking item text similarities according to their conceptual likeness. We tested the ability of four pretrained deep learning models to screen thousands of symptom description pairs for related content-a challenging task typically requiring expert panels. Models were tasked to predict symptom severity across four different inventories for 6,607 participants drawn from 16 international data sources. The STS approach achieved 74.8% accuracy across five tasks, outperforming other models tested. Correlation and factor analysis found the properties of the scales were broadly preserved under conversion. This work suggests that incorporating contextual, semantic information can assist expert decision-making processes, yielding broad gains for the harmonization of TBI assessment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.019
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.019
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0060.002
Science and technology studies0.0000.000
Scholarly communication0.0020.002
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.198
GPT teacher head0.421
Teacher spread0.223 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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Same venueJournal of NeurotraumaSame topicTraumatic Brain Injury ResearchFrench-language works237,207