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Record W4409300835 · doi:10.7150/thno.108552

Artificial intelligence in chronic kidney disease management: a scoping review

2025· review· en· W4409300835 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueTheranostics · 2025
Typereview
Languageen
FieldMedicine
TopicArtificial Intelligence in Healthcare and Education
Canadian institutionsUniversity of Manitoba
FundersNational Medical Research CouncilMedical Research Council
KeywordsKidney diseaseMedicineDiseaseIntensive care medicinePathologyBioinformaticsInternal medicineBiology

Abstract

fetched live from OpenAlex

Rationale: Chronic kidney disease (CKD) is a major public health problem worldwide associated with cardiovascular disease, renal failure, and mortality.To effectively address this growing burden, innovative solutions to management are urgently required.We conducted a scoping review to identify key use cases in which artificial intelligence (AI) could be leveraged for improving management of CKD.Additionally, we examined the challenges faced by AI in CKD management, proposed potential solutions to overcome these barriers.Methods: We reviewed 41 articles published between 2014-2024 which examined various AI techniques including machine learning (ML) and deep learning (DL), unsupervised clustering, digital twin, natural language processing (NLP) and large language models (LLMs) in CKD management.We focused on four areas: early detection, risk stratification and prediction, treatment recommendations and patient care and communication.Results: We identified 41 articles published between 2014-2024 that assessed image-based DL models for early detection (n = 6), ML models for risk stratification and prediction (n = 14) and treatment recommendations (n = 4), and NLP and LLMs for patient care and communication (n = 17).Key challenges in integrating AI models into healthcare include technical issues such as data quality and access, model accuracy, and interpretability, alongside adoption barriers like workflow integration, user training, and regulatory approval.Conclusions: There is tremendous potential of integrating AI into clinical care of CKD patients to enable early detection, prediction, and improved patient outcomes.Collaboration among healthcare providers, researchers, regulators, and industries is crucial to developing robust protocols that ensure compliance with legal standards, while minimizing risks and maintaining patient safety.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.592
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.225
GPT teacher head0.502
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it