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Record W4409305521 · doi:10.1101/2025.04.04.25325291

Predicting the stage of gastric cancer after gastrectomy based on machine learning algorithms

2025· preprint· en· W4409305521 on OpenAlexaff
Nayereh Abdali, Sajad Alavimanesh, Seyedeh Negin Hadisadegh

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldMedicine
TopicGastric Cancer Management and Outcomes
Canadian institutionsLakehead University
Fundersnot available
KeywordsGastrectomyStage (stratigraphy)CancerComputer scienceArtificial intelligenceAlgorithmMachine learningMedicineInternal medicineGeology

Abstract

fetched live from OpenAlex

Abstract Background Gastric cancer (GC) is the fourth most common cause of cancer death worldwide, with a 5-year survival rate of less than 40%. One of the most important methods for diagnosing stomach cancer is endoscopy, which is quite costly and invasive. The aim of this study was to develop machine learning-based diagnostic prediction models for the stage of GC. Objectives To create a highly accurate predictive model for the stage of GC in patients via a noninvasive method based on machine learning (ML). Methods In this study, data from 996 patients with GC after gastrectomy were utilized. The data were split into groups, trained and tested, and a ratio of 8:2 was used to develop different machine learning models. Furthermore, the six different machine learning algorithms used in predicting the stage of GC include decision tree (DT), K nearest neighbor (KNN), logistic regression (LR), naive Bayes (NB), random forest (RF), and support vector machine (SVM) methods. Results: The analysis of the demographic variables revealed statistically significant differences in the PLR and NLR and other parameters between the two groups of patients with stages I and III gastric cancer (P < 0.05). Results The analysis of demographic variables revealed statistically significant differences in the PLR, NLR, and other variables between the two groups of patients with stages I and III gastric cancer, with a significance level of P-value < 0.05. Moreover, these findings suggest that the KNN model in this study is one of the best models for predicting the stage of GC.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.006
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.288
Teacher spread0.269 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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