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Development of a methamphetamine chemical profiling program in Quebec, Canada for use in an intelligence perspective

2025· article· en· W4409322903 on OpenAlexaboutno aff
Marina Charest, Martine Lamarche, Pierre Esseiva

Bibliographic record

VenueForensic Science International · 2025
Typearticle
Languageen
FieldMedicine
TopicData-Driven Disease Surveillance
Canadian institutionsnot available
Fundersnot available
KeywordsProfiling (computer programming)MethamphetaminePerspective (graphical)Data scienceMedicineComputer sciencePsychiatryArtificial intelligence

Abstract

fetched live from OpenAlex

This paper describes a new method for the chemical profiling of seized methamphetamine tablets. This method was performed for the first time in Quebec, Canada, at the Laboratoire de sciences judiciaires et de médecine légale (LSJML, Provincial Forensic Laboratory). The main objective was to provide information related to the production and trafficking of methamphetamine tablets in the province of Quebec. Samples were analyzed using Gas Chromatography-Mass Spectrometry (GC-MS) and 12 relevant impurities were selected to establish the chemical class. Data were pretreated by the normalization to the sum of peak responses followed by the square roots. The Manhattan distance was then calculated between population of linked samples and unlinked samples. The method proved to efficiently discriminate between the two populations. A comprehensive database containing the profiles of all analyzed samples was established and continues to be updated. The database incorporates information about purity, chemical class, presence of cutting agents and physical characteristics of each specimen. If systematically applied, this methodology should highlight connections between ongoing cases and those stored in the database, as well as facilitate comparisons between preselected cases based on traditional police casework. Integrating the results of methamphetamine tablet chemical profiling with other pertinent law enforcement data will yield valuable tactical and operational intelligence as well as strategic intelligence. This project brings an additional tool to investigators with the differentiation of linked and unlinked methamphetamine specimens. Although further research is required to determine the tool's capacity to understand methamphetamine production and distribution networks, it shows potential for contributing to efforts against illicit production and trafficking in the province of Quebec, Canada.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.771
Threshold uncertainty score0.887

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.363
Teacher spread0.329 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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