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Record W4409422996 · doi:10.1016/j.idcr.2025.e02230

Holy water not so holy: Potential source of Elizabethkingia pneumonia and bacteremia in an immunocompromised host

2025· article· en· W4409422996 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueIDCases · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInfections and bacterial resistance
Canadian institutionsUniversity Health NetworkMcMaster UniversityUniversity of Toronto
Fundersnot available
KeywordsBacteremiaMedicinePneumoniaHost (biology)MicrobiologyVirologyIntensive care medicineAntibioticsBiologyInternal medicineGenetics

Abstract

fetched live from OpenAlex

Elizabethkingia species are Gram-negative, glucose-non-fermenting bacilli predominantly found in soil and water, with Elizabethkingia anophelis increasingly recognized as a human pathogen. E. anophelis has also been reported in hospital outbreaks, suggesting the potential role of contaminated institutional water sources. Conventional microbiological methods often lead to misidentifying this pathogen for other members of the genus Elizabethkingia , suggesting a role for molecular methods for identification. We report a 67-year-old female who developed multiorgan failure requiring intensive care unit admission and mechanical ventilation while being treated with chemotherapy for Burkitt lymphoma. She developed pneumonia with Gram-negative bacilli isolated from her endotracheal aspirate culture, later identified as E. anophelis . She later developed bacteremia due to the same pathogen, which was confirmed by MALDI-TOF and whole genome sequencing. Waterborne transmission via holy water administration was postulated to be potential source of infection. Our case report highlights that E. anophelis may cause significant infection and should not be disregarded as contaminant, especially in immunosuppressed individuals. As a waterborne pathogen that may be brought into hospital environments, emphasis on educating family members, close nursing monitoring, and reporting of suspected, unsupervised manipulation of medical equipment should be undertaken to prevent contamination by this organism from outside sources.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.188
Threshold uncertainty score0.390

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.239
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it