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Record W4409465448 · doi:10.1080/10643389.2025.2488808

Recent advances in layered double hydroxides for pharmaceutical wastewater treatment: A critical review

2025· review· en· W4409465448 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCritical Reviews in Environmental Science and Technology · 2025
Typereview
Languageen
FieldMaterials Science
TopicLayered Double Hydroxides Synthesis and Applications
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsLayered double hydroxidesWastewaterEnvironmental scienceWaste managementChemistryEngineeringEnvironmental engineeringHydroxideInorganic chemistry

Abstract

fetched live from OpenAlex

In recent decades, pharmaceuticals, lauded for saving millions of lives, have surfaced as a new class of environmental contaminants. These compounds, originating primarily from hospital and industrial settings, often resist traditional treatment technologies and can persist in the environment for extended periods. The scarcity of water resources underscores the urgent need for innovative strategies for the effective management of pharmaceutical wastewater. Recently, layered double hydroxides (LDHs) have garnered considerable attention for their application in the remediation of pharmaceutical wastewater. This review explores the recent advancements in LDH-based adsorbents and membranes for pharmaceutical wastewater treatment. LDHs demonstrate superior adsorption capabilities due to their intercalation properties and structural versatility, effectively removing pharmaceutical contaminants such as antibiotics and anti-inflammatory drugs. Moreover, LDH-modified membranes enhance separation efficiency by improving permeability, selectivity, and fouling resistance. Advanced analytical techniques, including machine learning and synchrotron radiation, have provided deeper insights into the LDH mechanisms. However, challenges such as metal leaching, low mechanical durability, and limited scalability remain critical hurdles. Future research should focus on optimizing LDH stability, integrating adsorption with membrane separation techniques, and exploring hybrid treatment strategies. The recovery of valuable pharmaceuticals through LDH-based systems also presents a sustainable approach to wastewater management. This review highlights the potential of LDHs in pharmaceutical wastewater treatment while identifying key points for further development to enhance their practicality and large-scale application.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.972
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0010.001
Science and technology studies0.0000.003
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.071
GPT teacher head0.405
Teacher spread0.334 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it