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Record W4409500001 · doi:10.17269/s41997-025-01027-3

Description and evaluation of a national humanitarian opioid poisoning education and naloxone distribution program

2025· article· en· W4409500001 on OpenAlexafffundvenueabout
Bruna dos Santos, Alexandra Kubica, Anna Maria Subic, Nick Rondinelli, Ben Evans-Durán, Don Marentette, Joanna Muise, Kevin Paes, Meghan Riley, Samiya Bhuiya, Jeannene Crosby, Keely McBride, Joe Salter, Aaron Orkin

Bibliographic record

VenueCanadian Journal of Public Health · 2025
Typearticle
Languageen
FieldMedicine
TopicOpioid Use Disorder Treatment
Canadian institutionsCanadian Red Cross SocietyCanadian Heart Research CentrePublic Health OntarioUniversity of Toronto
FundersHealth Canada
KeywordsHarm reduction(+)-NaloxoneOpioid overdoseMedicineFocus groupIndigenousOpioidPoison controlSuicide preventionPsychologyNursingMedical emergencyPublic healthSociology

Abstract

fetched live from OpenAlex

SETTING: Canada's opioid poisoning crisis claimed 49,105 lives from January 2016 to June 2024. Opioid poisoning education and naloxone distribution programs can reduce fatalities, although access remains inconsistent across Canada. These programs have mostly been delivered in person through community, healthcare, and social service agencies. INTERVENTION: The Canadian Red Cross implemented a national, free, bilingual, virtually accessible, opioid harm reduction program, leveraging its experience in first aid education and community relationships as a humanitarian organization. The Opioid Harm Reduction program launched three new courses and added opioid poisoning content to four existing courses. Courses were adapted continually based on the feedback of people with lived experience of drug use and program participants. The program was delivered from January 2021 to March 2024 and evaluated through quantitative and qualitative methods. OUTCOMES: The program delivered 1,386,995 trainings and successfully reached diverse groups, including those from Indigenous (5.3%) and rural (25.2%) communities, but had an underrepresentation of men (34.3%) and individuals working in the construction industry (4.8%). Participants' self-reported knowledge and confidence in responding to opioid poisoning increased across all courses (p < 0.001), particularly for learners without prior training. In total, 24,098 intranasal naloxone kits were distributed, 60.4% to Ontario, Manitoba, and British Columbia. Most participant feedback (82%) received was positive, highlighting the course's simplicity and focus on stigma. IMPLICATIONS: The Canadian Red Cross Opioid Harm Reduction program advanced harm reduction, increased awareness of opioid poisonings, and situated the response to the opioid poisoning crisis as a community health effort.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.010
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.364
Threshold uncertainty score0.732

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0100.010
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0070.002
Scholarly communication0.0020.001
Open science0.0040.003
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.069
GPT teacher head0.373
Teacher spread0.304 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes4
Has abstractyes

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