MétaCan
Menu
Back to cohort
Record W4409529754 · doi:10.1016/j.lanwpc.2025.101548

Changing age profile and incidence of injecting drug use initiation among people in Australia who inject drugs: evidence from two national repeated cross-sectional studies

2025· article· en· W4409529754 on OpenAlexafffund
Olivia Price, Lisa Maher, Amy Peacock, Farzaneh Zolala, Louisa Degenhardt, Paul Dietze, Sarah Larney, Seraina Agramunt, Samantha Colledge‐Frisby, Bradley Mathers, Dan Lewer, Rachel Sutherland

Bibliographic record

VenueThe Lancet Regional Health - Western Pacific · 2025
Typearticle
Languageen
FieldMedicine
TopicHIV, Drug Use, Sexual Risk
Canadian institutionsUniversité de MontréalCentre Hospitalier de l’Université de Montréal
FundersNational Drug and Alcohol Research CentreNational Health and Medical Research CouncilFonds de Recherche du Québec - SantéDepartment of Health and Aged Care, Australian GovernmentNational Institute for Health and Care Research
KeywordsIncidence (geometry)Cross-sectional studyMedicineDrugDemographyEnvironmental healthPharmacologySociologyPathology

Abstract

fetched live from OpenAlex

Background: The age of people who inject drugs appears to be increasing in some high-income countries. We aimed to explore trends in the age of people injecting and recently starting to inject drugs in Australia, and to model incidence of initiation over time. Methods: We obtained data from the Illicit Drug Reporting System (IDRS) and the Australian Needle Syringe Program Survey (ANSPS), which comprise annual cross-sectional surveys with people who inject drugs (2000-2019). Outcome measures were current age, age of initiation, and time since initiation (both surveys), and drug first injected (IDRS only). We estimated time trends in age using quantile regression. We used the relative number of people initiating injecting drug use each year and existing population size estimates to model incidence of initiation. Findings: In total, 58,465 interviews with people who reported injecting drugs in the past month (33.7% women) were included. In both surveys, the median age increased over the study period (IDRS: 28-43 years; ANSPS 28-44 years). The median time since initiation also increased over the study period (IDRS: 8-22.5 years; ANSPS: 9-24 years), and the median age of initiation increased with calendar year of initiation (IDRS: 18-34 years; ANSPS: 20-30 years). Women tended to be younger and commence injecting drug use at a younger age than men. Modelling suggested that similar numbers of people injected drugs for the first time each year from 1980 (national estimates of 15,570 and 17,020 new initiates using IDRS and ANSPS data, respectively) to 1996 (IDRS: 16,360; ANSPS: 22,300 new initiates), followed by a decisive decline in incidence until 2012 (IDRS: 1110; ANSPS: 1830), whereafter it has fluctuated but remained low. Meth/amphetamine was consistently the predominant drug injected at initiation among IDRS participants, although there were peaks in heroin as the drug injected at initiation in the early 1980s and mid-1990s. Interpretation: In 2019, most people who were injecting drugs in Australia were part of a cohort that began injecting in the 1980s or 1990s. Consequently, the population was older and had been injecting drugs for longer compared to those injecting drugs in 2000. This has implications for health service delivery to people who inject drugs, with increasing age likely to be accompanied by a rise in chronic health conditions and an increase in injecting duration potentially resulting in higher incidence of injecting-related injuries and diseases. Funding: Australian Government Department of Health and Aged Care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.041
Threshold uncertainty score0.815

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.212
GPT teacher head0.467
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes2
Has abstractyes

Explore more

Same venueThe Lancet Regional Health - Western PacificSame topicHIV, Drug Use, Sexual RiskFrench-language works237,207