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Record W4409593124 · doi:10.1038/s42004-025-01519-w

BioStruct-Africa’s capacity building workshops as a model for advancing the emerging community of structural biologists in Africa

2025· article· en· W4409593124 on OpenAlex
Safiétou Sankhe, Fatoumata FOFANA, Walid Heiba, Oludare M. Ogunyemi, Kabo Masisi, Irene Muiruri, Eunice A Abaah, Arnaud Tepa, Chi Tchampo Fru, J. Johnson, Claire V Tchuenguia, Nelly M.T. Tatchou-Nebangwa, Desmon T Tsafack, Koloko Brice Landry, Tessy-Koko Kulu-Abi, Ivana Ngounou, Toussaint S D Sovegnon, Rolin Mitterran N Kamga, Mersimine Kouamo, Yeshimebet C Getahun, Aurélien F. A. Moumbock, Katharina Cramer, Nicolas Rüffin, Louise Djapgne, Piotr Sliz, Jamaine Davis, Michel Fodje, Julia J. Griese, Emmanuel Nji

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCommunications Chemistry · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetics, Bioinformatics, and Biomedical Research
Canadian institutionsCanadian Light Source (Canada)
FundersDirectorate for Biological SciencesVetenskapsrådetKwame Nkrumah University of Science and TechnologyAlexandria UniversityAlbert-Ludwigs-Universität FreiburgSvenska Forskningsrådet FormasWellcome TrustUniversité de FribourgWellcomeGoogleCompany of BiologistsBotswana International University of Science and Technology
KeywordsGeographyPolitical science

Abstract

fetched live from OpenAlex

Structural biology is crucial in understanding disease mechanisms and in driving drug and vaccine development—applications that are particularly relevant to Africa’s challenges—yet Africa faces significant barriers to advancing structural biology. Here, the authors outline a recent capacity building workshop run by BioStruct-Africa, focused on training of artificial intelligence tools such as AlphaFold, designed to foster a highly skilled community of structural biologists in Africa. Structural biology is crucial in understanding disease mechanisms and in driving drug and vaccine development—applications that are particularly relevant to Africa’s challenges—yet Africa faces significant barriers to advancing structural biology. Here, the authors outline a recent capacity building workshop run by BioStruct-Africa, focused on training of artificial intelligence tools such as AlphaFold, designed to foster a highly skilled community of structural biologists in Africa.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.302
Threshold uncertainty score0.512

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0020.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.054
GPT teacher head0.344
Teacher spread0.290 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it