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Record W4409632445 · doi:10.7326/annals-24-01967

Risk for Stroke After Newly Diagnosed Atrial Fibrillation During Hospitalization for Other Primary Diagnoses

2025· article· en· W4409632445 on OpenAlexaffabout
Husam Abdel‐Qadir, Madison Gunn, Jiming Fang, Tomi Odugbemi, Irene Jeong, Peter C. Austin, Paul Dorian, Cynthia A. Jackevicius, Douglas S. Lee, Sheldon M. Singh, Karen Tu, Dennis T. Ko

Bibliographic record

VenueAnnals of Internal Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicAtrial Fibrillation Management and Outcomes
Canadian institutionsHealth Sciences CentreNorth York General HospitalSunnybrook Health Science CentreWestern UniversityWomen's College HospitalUniversity of TorontoUniversity Health Network
Fundersnot available
KeywordsMedicineAtrial fibrillationStroke (engine)Medical diagnosisEmergency medicineStroke riskInternal medicineCardiologyPediatricsIntensive care medicineIschemic strokeMedical emergencyRadiology

Abstract

fetched live from OpenAlex

BACKGROUND: Atrial fibrillation (AF) that is first diagnosed during hospitalization for other causes can subside with resolution of the inciting stressor. OBJECTIVE: To describe the risk for stroke after newly diagnosed AF during hospitalization for other causes. DESIGN: Population-based retrospective cohort study. SETTING: Ontario, Canada. PARTICIPANTS: Patients aged 66 years or older discharged alive from the hospital between April 2013 and March 2023 with a first diagnosis of AF. INTERVENTION: Newly diagnosed AF during hospitalization for other causes, categorized into cardiac medical, noncardiac medical, cardiac surgical, and noncardiac surgical. MEASUREMENTS: The primary outcome was hospitalization for stroke. The cumulative incidence function was used to estimate crude incidence, censoring on anticoagulant dispensation. Inverse probability of censoring weights were used to account for informative censoring. RESULTS: -VA scores of 5 to 8. LIMITATION: Long-standing AF may have been misclassified as newly diagnosed, leading to overestimation of stroke risk. CONCLUSION: -VA scores greater than 4 approximated the 2% threshold commonly used to initiate anticoagulation in AF. PRIMARY FUNDING SOURCE: Canadian Cardiovascular Society.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.237
Threshold uncertainty score0.471

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.358
Teacher spread0.321 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes2
Has abstractyes

Explore more

Same venueAnnals of Internal MedicineSame topicAtrial Fibrillation Management and OutcomesFrench-language works237,207