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Record W4409664886 · doi:10.1038/s41598-025-96839-1

Genomic prediction and genetic parameter estimation for unsaturated and saturated fatty acids in Canadian dairy cattle

2025· article· en· W4409664886 on OpenAlexafffundabout
Sunday O. Peters, Kadir Kızılkaya, Eveline M. Ibeagha‐Awemu, Xin Zhao

Bibliographic record

VenueScientific Reports · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic and phenotypic traits in livestock
Canadian institutionsMcGill UniversityAgriculture and Agri-Food Canada
FundersNatural Sciences and Engineering Research Council of CanadaTürkiye Bilimsel ve Teknolojik Araştırma KurumuBerry College
KeywordsEstimationDairy cattleGenomic selectionBiologyCattle DiseasesGeneticsBiotechnologyComputational biologyGeneGenotypeEconomicsSingle-nucleotide polymorphism

Abstract

fetched live from OpenAlex

The current study aimed to obtain the estimates of heritabilities and genetic correlations and the prediction abilities and accuracy of Bayesian GBLUP and Bayesian alphabet (BayesA, BayesB, BayesC) models for total and individual monounsaturated, polyunsaturated and saturated fatty acids from Canadian Holstein cows by using genome-wide SNP markers from genotyping-by-sequencing method. The heritability estimates were obtained from Bayesian GBLUP and Bayesian alphabet models. They ranged from 0.61 to 0.67 for total monounsaturated, from 0.35 to 0.45 for polyunsaturated and from 0.51 to 0.60 for saturated fatty acids, respectively. For thirty-three individual monounsaturated, polyunsaturated and saturated fatty acids, the heritability estimates ranged from 0.27 to 0.69 for individual monounsaturated, from 0.27 to 0.68 for individual polyunsaturated and from 0.35 to 0.69 for individual saturated fatty acids. These results indicated that total and individual monounsaturated, polyunsaturated and saturated fatty acids were under moderate genetic control and can be improved through genomic selection. The estimates of genetic correlations among total and individual monounsaturated, polyunsaturated and saturated fatty acids showed a moderate to high genetic relationships and pointed out the need for consideration of genetic relationships in successful genomic selection for fatty acids traits. The accuracies of BayesC and BayesA models were similar and better than that of GBLUP and BayesB models which indicated that fatty acids were determined by many genes having non-null effects, which are assumed to follow a univariate or multivariate Student's t distribution.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.248
Threshold uncertainty score0.498

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.233
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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