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Record W4409674163 · doi:10.61373/gp025k.0023

Jeremie Poschmann: Data-driven discovery in human diseases through multi-omics profiling of the circulating immune system

2025· article· en· W4409674163 on OpenAlexaboutno aff
Jérémie Poschmann

Bibliographic record

VenueGenomic psychiatry : · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBioinformatics and Genomic Networks
Canadian institutionsnot available
Fundersnot available
KeywordsProfiling (computer programming)Computational biologyImmune systemOmicsComputer scienceData scienceBiologyBioinformaticsImmunology

Abstract

fetched live from OpenAlex

Dr. Jeremie Poschmann leads a research group at INSERM and Université de Nantes, where he investigates the human immune system with a focus on the circulating immune compartment. His work combines multi-omics and data-driven approaches to uncover immune mechanisms that influence disease susceptibility and patient outcomes, particularly in infectious and psychiatric conditions. Trained originally as a nurse, Dr. Poschmann entered science driven by a deep curiosity for the unresolved complexities of human biology. His career has taken him through Germany, Belgium, Canada, Singapore, the UK, and France, shaping his collaborative and cross-disciplinary mindset. A self-taught bioinformatician, he values independence in research and actively fosters a diverse and inclusive team. In this Genomic Press Interview, he reflects on pivotal moments in his journey including an early fascination with genome-wide discovery and shares how pre-existing immune states may help explain why individuals respond differently to disease exposure. Outside the lab, he finds balance through surfing and chess, which keeps his thinking sharp. Committed to translating research into real-world impact, Dr. Poschmann is equally passionate about mentoring emerging scientists and building a culture that supports innovation and integrity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.012
metaresearch head score (Gemma)0.028
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.012
Threshold uncertainty score0.061

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0120.028
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0010.003
Scholarly communication0.0050.004
Open science0.0010.002
Research integrity0.0020.006
Insufficient payload (model declined to judge)0.0080.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.266
Teacher spread0.252 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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