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Record W4409677661 · doi:10.1101/2025.04.14.648789

Early warning signals do not predict a warming-induced experimental epidemic

2025· preprint· en· W4409677661 on OpenAlexaff
Madeline Jarvis‐Cross, Devin Kirk, Leila Krichel, Pepijn Luijckx, Péter K. Molnár, Martin Krkošek

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldEnvironmental Science
TopicEcosystem dynamics and resilience
Canadian institutionsThe Scarborough HospitalUniversity of British ColumbiaUniversity of Toronto
Fundersnot available
KeywordsWarning systemEnvironmental scienceClimatologyEconometricsComputer scienceMeteorologyGeographyEconomicsGeologyTelecommunications

Abstract

fetched live from OpenAlex

Abstract Climate change can impact the rates at which parasites are transmitted between hosts, ultimately determining if and when an epidemic will emerge. As such, our ability to predict climate-mediated epidemic emergence will become increasingly important in our efforts to prepare for and mitigate the effects of disease outbreaks on ecological systems and human health. Theory suggests that statistical signatures termed “early warning signals” (EWS), can function as predictors of disease emergence. Here, we analyze experimental and simulated time series of disease spread within populations of the model disease system Daphnia magna – Ordospora colligata for EWS of epidemic emergence. In this system, low temperatures prevent disease emergence, while sufficiently high temperatures force the system through a critical transition to an epidemic state. We found that EWS of epidemic emergence were nearly as likely to be detected in populations maintained at a sub-epidemic temperature as they were to be detected in populations subjected to a warming treatment that induced epidemic spread. Our findings suggest that the detection of false positives may limit the reliability of EWS as predictors of climate-mediated epidemic emergence.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.229
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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