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Record W4409731477 · doi:10.1371/journal.pone.0320588

Effects of repeated gravity changes during parabolic flight: Evidence of the need to assist space tourists to outer space

2025· article· en· W4409731477 on OpenAlexaff
Barbara Le Roy, Charles Martin‐Krumm, Vincent Beauchamps, Adrien Jimenez, Louise Giaume, Sandrine Jacob, Aude Voilque, Ouamar Ferhani, Ellemarije Altena, Marion Trousselard

Bibliographic record

VenuePLoS ONE · 2025
Typearticle
Languageen
FieldMedicine
TopicSpaceflight effects on biology
Canadian institutionsArtificial Intelligence in Medicine (Canada)
Fundersnot available
KeywordsHeart rateWeightlessnessPsychologyHeart rate variabilityCognitionSensory systemPhysical medicine and rehabilitationMedicineAudiologyCognitive psychologyInternal medicineBlood pressureNeuroscience

Abstract

fetched live from OpenAlex

In the era of space tourism, walking in the steps of Neil Armstrong has never been more real. Future space tourists will have to face the harshness of the environment, especially the travel, and adapt quickly for their own safety. This issue raises both the question of preparation and the impact of such a journey on novice populations who have not been selected for their physical and cognitive abilities. The objectives of the study are (1) to investigate the impact of space travel on psychophysiological and sensory responses during a parabolic flight experience; (2) to assess recovery from this experience one week later; and (3) to evaluate the relevance of high parasympathetic functioning at baseline as a biomarker of adaptation. Seventeen healthy participants were enrolled in the 79th ESA Parabolic Flight Campaign on board the Airbus A310. Psychological, physiological, and sensory responses were measured at different times from the day before the 3h-flight (baseline) to one week after the flight (recovery). Labels were allocated to two groups according to their parasympathetic functioning at baseline: high parasympathetic (HP) profile and low parasympathetic (LP) profile. At the psychological level, those with an HP profile have a higher coping acceptation and a higher level of interoceptive awareness than the LP profile, except for sleep quality. At the physiological and exteroceptive level, they have a higher heart rate variability, preserved identification of odors and a predisposition to a more adaptive postural response postflight. Nevertheless, postural stability is affected in both profiles, particularly during visual deprivation, while their heart rate variability is increased in both linear and non-linear components. Nevertheless, our results reveal that the recovery constitutes a critical period. Flyers have a decrease of interoceptive awareness and emotions, especially the HP profile. Although the LP profile reported a better subjective sleep quality, both profiles decreased their sleep quality. These results raise the question of the risks that may be induced by space tourism. They highlight two major outcomes: (1) travel of future space tourists does not seem to be at risk as long as the individuals are qualified and fit for the flight and adaptation may be improved by targeting parasympathetic functioning; (2) level of experience has no impact on the psychophysiological and sensory responses. The results highlight the need to monitor the crews over several days and/or to include in the preparation a module allowing them to be prepared for the postflight period and the return to life on Earth. Beyond this, these results contribute to enriching our knowledge of the human challenge of confronting space travel constraints.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.299
Threshold uncertainty score0.684

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.274
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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