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Record W4409734425

Resolution of Pediatric Mandibular Langerhans Cell Histiocytosis Post-Biopsy.

2025· article· en· W4409734425 on OpenAlexaff
Olivia Dalzell, Paniz Haghighi, Frederic Rochon, Anita Nagy, Gabriella Amneris Garisto

Bibliographic record

VenuePubMed · 2025
Typearticle
Languageen
FieldMedicine
TopicHistiocytic Disorders and Treatments
Canadian institutionsHospital for Sick Children
Fundersnot available
KeywordsLangerhans cell histiocytosisMedicineBiopsyHistiocytosisPathology
DOInot available

Abstract

fetched live from OpenAlex

Langerhans cell histiocytosis (LCH) is a rare disease marked by the proliferation of Langerhans cells and the destruction of tissue. LCH can be limited to the oral cavity where it can present with gingival bleeding, swelling, tooth mobility and bone loss. This case report describes a 13-year-old male with LCH who presented with a one-month history of painful jaw swelling. Clinical examination revealed a firm, ulcerated mass adjacent to the mandibular right second premolar. Biopsy and subsequent histopatho- logic examination confirmed LCH. The lesion resolved spontaneously post-biopsy and the patient remains disease-free. Recognizing oral manifestations of LCH in dental practice is crucial for prompt diagnosis, appropriate multidisciplinary management and improving the survival rates and future quality of life for children with LCH.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.219
Teacher spread0.209 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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