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Record W4409882484 · doi:10.32388/hisnx4.2

A Population-Based Model for Rationing COVID-19 Vaccine

2023· preprint· en· W4409882484 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueQeios · 2023
Typepreprint
Languageen
FieldMedicine
TopicInfluenza Virus Research Studies
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakVirologyPopulationEconomicsMedicineEnvironmental healthOutbreakInternal medicineInfectious disease (medical specialty)

Abstract

fetched live from OpenAlex

BACKGROUND As COVID-19 vaccines develop, methods for identifying vulnerability within groups for prioritized vaccination remain unestablished. This paper presents a novel approach based on population-based analysis of viral pneumonia vulnerability as an example. METHODS The analysis employed an anonymous, 16-year, population dataset (n = 768,460) consisting of International Classification of Diseases (ICD-9) diagnoses, demographics, and dates identifying those with viral pneumonia and permitting linkage of these individuals to all their associated diagnoses for the calculation of odds ratios and proportions of disorders before and after the index viral pneumonia diagnosis. RESULTS Females and males had results of differing magnitude. For those with viral pneumonia, the mean number of diagnoses was greater in both the subsample and the whole sample, with associated diagnoses arising about 4 years on average before the viral pneumonia index diagnosis. Within the subsample, compared to those without, the temporal analysis revealed distinct over-representation for those with viral pneumonia at visit one and over the first fifty visits. Further, those with viral pneumonia had diagnoses not represented in the group without viral pneumonia. CONCLUSIONS The population-based analysis of temporal hyper-morbidity may be a viable and economical approach to identifying viral pneumonia vulnerability. The approach presented in this paper may provide an economical means of identifying vulnerability to COVID-19 in regions where comparable data are available for analysis. Rational approaches may optimize vaccination and help to limit the spread of the disease and to some extent alleviate the health service burden.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.872
Threshold uncertainty score0.964

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.303
GPT teacher head0.481
Teacher spread0.178 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it