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Record W4409886550 · doi:10.1016/j.jgar.2025.04.006

Standardizing multidrug resistance definitions and visualizations to support surveillance across One Health

2025· article· en· W4409886550 on OpenAlexaff
Claudia Cobo Angel, Ava Glowney, Abdolreza Mosaddegh, Kurtis E. Sobkowich, Zvonimir Poljak, J. Scott Weese, Casey L. Cazer

Bibliographic record

VenueJournal of Global Antimicrobial Resistance · 2025
Typearticle
Languageen
FieldImmunology and Microbiology
TopicAntibiotic Use and Resistance
Canadian institutionsUniversity of Guelph
FundersAnimal and Plant Health Inspection Service
KeywordsResistance (ecology)Multiple drug resistanceData scienceComputer scienceEnvironmental healthMedicineDrug resistanceBiologyGenetics

Abstract

fetched live from OpenAlex

OBJECTIVE: This study aimed to understand the current use of visualizations for multidrug resistance (MDR) data across the One Health spectrum and the visualization preferences and definitions of MDR used by antimicrobial resistance experts, with emphasis on the animal health sector of One Health, which lacks standardized MDR definitions. METHODS: A rapid scoping review was conducted to synthesize current approaches to visualize MDR. Six databases and grey literature were searched with antimicrobial, resistance, surveillance, and figure or dashboard terms. An active machine learning model was used for the initial screening of references. An online survey was distributed to self-identified antimicrobial resistance experts, including questions about respondents' country of employment, job position, definitions of MDR, and preferences for MDR metrics and visualizations. RESULTS: Bar charts, visual antibiograms, heat maps, and network graphs were the most common visualizations employed in peer-reviewed publications, websites, and reports. Survey respondents preferred simplistic visualizations, such as line graphs and heat maps. Respondents used a variety of MDR definitions, although resistance to three or more antimicrobial categories was the most common. Some respondents advocated for the exclusion of intrinsic resistance in the definition, while others argued for its inclusion. CONCLUSIONS: Despite historic proposals for standardizing international definitions of MDR, a lack of consensus remains. Respondents also expressed different preferences for MDR visualizations. Some visualizations currently in use, such as network graphs, are complex and may be challenging to interpret. Harmonization of MDR definitions and optimization of visualizations are essential to facilitate comparisons across populations and studies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.315
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.322
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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