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Record W4409912700 · doi:10.1098/rsos.250032

Edge-based modelling for disease transmission on random graphs: an application to mitigate a syphilis outbreak

2025· article· en· W4409912700 on OpenAlexafffundabout
Sicheng Zhao, Sahar Saeed, Megan Carter, Bradley P. Stoner, Maggie Hoover, F. M. G. Magpantay

Bibliographic record

VenueRoyal Society Open Science · 2025
Typearticle
Languageen
FieldPhysics and Astronomy
TopicComplex Network Analysis Techniques
Canadian institutionsKingston Health Sciences CentreQueen's UniversityMcMaster University
FundersNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health ResearchCanada Foundation for Innovation
KeywordsOutbreakSyphilisDisease transmissionTransmission (telecommunications)Computer scienceRandom graphDiseaseEnhanced Data Rates for GSM EvolutionVirologyBiologyTheoretical computer scienceMedicineArtificial intelligenceGraphTelecommunicationsHuman immunodeficiency virus (HIV)

Abstract

fetched live from OpenAlex

Edge-based network models, especially those based on bond percolation methods, can be used to model disease transmission on complex networks and accommodate social heterogeneity while keeping tractability. Here we present an application of an edge-based network model to the spread of syphilis in the Kingston, Frontenac and Lennox & Addington region of southeastern Ontario, Canada. We compared the results of using a network-based susceptible-infectious-recovered (SIR) model to those generated from using a traditional mass action SIR model. We found that the network model yields very different predictions, including a much lower estimate of the final epidemic size. We also used the network model to estimate the potential impact of introducing a rapid syphilis point of care test and treatment intervention strategy that has recently been implemented by the public health unit to mitigate syphilis transmission.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.067
Threshold uncertainty score0.132

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.312
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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