MétaCan
Menu
Back to cohort
Record W4409957776 · doi:10.3389/fphys.2025.1605779

Case report: Biphasic autonomic response in decompression sickness: HRV and sinoatrial findings

2025· article· en· W4409957776 on OpenAlexfundno aff
Gerald J. Schmitz

Bibliographic record

VenueFrontiers in Physiology · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiovascular and Diving-Related Complications
Canadian institutionsnot available
FundersFrontiers Foundation
KeywordsMedicineAutonomic functionAutonomic nervous systemSinoatrial nodeHeart rate variabilityCardiologyInternal medicineNeuroscienceAnesthesiaHeart ratePsychologyBlood pressure

Abstract

fetched live from OpenAlex

Background: Decompression sickness (DCS) may involve neurological and cardiovascular systems, but cardiac autonomic dysfunction is rarely documented. Heart rate variability (HRV) can provide insight into autonomic modulation in such cases, particularly when incorporating advanced nonlinear and dynamic techniques. Case: We present a 35-year-old recreational diver who developed neurological DCS and persistent bradycardia following multiple consecutive dives. Neurological symptoms resolved with hyperbaric oxygen therapy (HBOT), but bradyarrhythmias persisted, prompting continuous monitoring. Methods: HRV was assessed using time-domain, frequency-domain, nonlinear, and dynamic analyses during HBOT and over two 24-h Holter recordings. Principal Dynamic Mode (PDM) analysis was employed to characterize autonomic control dynamics beyond conventional spectral markers. Results: during HBOT), SD1/SD2 ratio declined from 0.52 to 0.12, suggesting selective vagal withdrawal. PDM analysis showed a low PDM2/PDM1 ratio (0.42), consistent with preserved beat-to-beat vagal responsiveness but impaired long-range autonomic integration. Conclusion: This case illustrates a biphasic autonomic pattern in DCS-initial parasympathetic dominance followed by sympathetic tilt and desynchronization. Advanced nonlinear and dynamic HRV analysis revealed regulatory disturbances not captured by traditional methods, supporting its role in post-dive assessment and autonomic monitoring.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.275
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueFrontiers in PhysiologySame topicCardiovascular and Diving-Related ComplicationsFrench-language works237,207