Liver alterations found in patients with inflammatory bowel disease in a tertiary care center.
Bibliographic record
Abstract
Inflammatory bowel disease (IBD) encompasses two main conditions: Crohn's disease (CD) and ulcerative colitis (UC); the association between these diseases and liver diseases has been described. The objective of this work is to report the frequency of these alterations in a tertiary hospital. Observational, retrospective, descriptive, case series type. Patients with a diagnosis of IBD were included, including its two variants, CD and UC. An intentional search was carried out for alterations in the liver biochemical profile, findings in imaging methods and their clinical correlation, primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), autoimmune hepatitis (AIH), among other anatomical alterations. Qualitative data are expressed in percentages and quantitative data in mean±SD. 62 patients were included, of which 31 were men and 31 were women, with a mean age of 42.74±15.47 years. Within this universe, there were 22 patients with CD (35.4%), 40 patients with UC (64.5%) who, according to the Montreal classification, were classified as E1=4 patients (10%), E2=12 patients (30%), E3=24 patients (60%). There were 16 patients (25.8%) who had some reported liver alteration, of which 8 (12.9%) with autoimmune liver diseases, 5 with PSC (8.06%), 2 with PBC (3.22%), 1 with HAI (1.61%). When intentionally searching for liver morphological alterations and as an incidental finding, they were found 3 (4.83%) simple hepatic cysts, 1 (1.61.%) hepatic hemangioma, and finally, 2 (3.22%) hepatitis C virus (HCV) infections. IBD is commonly associated with autoimmune liver disorders. Likewise, the CUCI-PBC and CUCI-HAI relationship was found, which agrees with the international literature and is extrapolated with the population studied. Other incidental findings are also frequent, especially the high frequency of HCV compared to the general population.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".