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Escalate Prognosis of Parkinson’s Disease Employing Wavelet Features and Artificial Intelligence from Vowel Phonation

2025· article· en· W4410004216 on OpenAlexaff
Rumana Islam, Mohammed Tarique

Bibliographic record

VenueBioMedInformatics · 2025
Typearticle
Languageen
FieldMedicine
TopicVoice and Speech Disorders
Canadian institutionsUniversity of Windsor
Fundersnot available
KeywordsPhonationVowelWaveletSpeech recognitionParkinson's diseaseAudiologyArtificial intelligenceDiseaseMedicineComputer sciencePathology

Abstract

fetched live from OpenAlex

Background: This work presents an artificial intelligence-based algorithm for detecting Parkinson’s disease (PD) from voice signals. The detection of PD at pre-symptomatic stages is imperative to slow disease progression. Speech signal processing-based PD detection can play a crucial role here, as it has been reported in the literature that PD affects the voice quality of patients at an early stage. Hence, speech samples can be used as biomarkers of PD, provided that suitable voice features and artificial intelligence algorithms are employed. Methods: Advanced signal-processing techniques are used to extract audio features from the sustained vowel ‘/a/’ sound. The extracted audio features include baseline features, intensities, formant frequencies, bandwidths, vocal fold parameters, and Mel-frequency cepstral coefficients (MFCCs) to form a feature vector. Then, this feature vector is further enriched by including wavelet-based features to form the second feature vector. For classification purposes, two popular machine learning models, namely, support vector machine (SVM) and k-nearest neighbors (kNNs), are trained to distinguish patients with PD. Results: The results demonstrate that the inclusion of wavelet-based voice features enhances the performance of both the SVM and kNN models for PD detection. However, kNN provides better accuracy, detection speed, training time, and misclassification cost than SVM. Conclusions: This work concludes that wavelet-based voice features are important for detecting neurodegenerative diseases like PD. These wavelet features can enhance the classification performance of machine learning models. This work also concludes that kNN is recommendable over SVM for the investigated voice features, despite the inclusion and exclusion of the wavelet features.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.288
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations2
Published2025
Admission routes1
Has abstractyes

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