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Record W4410014768 · doi:10.1016/j.pmedr.2025.103093

Characteristics of persons with multiple sclerosis covered by public drug insurance in a Quebec Birth Cohort

2025· article· en· W4410014768 on OpenAlexafffundabout
Yasmine Sadou, Miceline Mésidor, Marie‐Claude Rousseau

Bibliographic record

VenuePreventive Medicine Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicMultiple Sclerosis Research Studies
Canadian institutionsCentre Hospitalier de l’Université de MontréalUniversité de MontréalInstitut National de la Recherche Scientifique
FundersCanadian Institutes of Health ResearchMinistère de l'Éducation, du Loisir et du Sport QuébecMitacsFonds de Recherche du Québec - SantéMultiple Sclerosis Society of CanadaCanadian Cancer SocietyCanada Foundation for Innovation
KeywordsMedicineCohortMultiple sclerosisDrugPublic health insuranceCohort studyPublic healthHealth insuranceFamily medicineEnvironmental healthDemographyPsychiatryInternal medicinePolitical scienceHealth careNursingLaw

Abstract

fetched live from OpenAlex

Objective: People living with multiple sclerosis use medications for several indications, but little is known about their prescription drug use in Quebec, notably because the public drug insurance covers only part of the population. We compared the characteristics of those with public drug insurance to those privately covered. Methods: In a cohort of persons born in 1970-1974, we identified those living with multiple sclerosis by applying a validated algorithm to administrative health data. Individuals with public coverage were those who had at least one covered period after their date of diagnosis between January 1, 1997, and December 31, 2014. We used descriptive statistics to compare sociodemographic and healthcare utilization characteristics by type of coverage. Results: Among the 1363 persons living with multiple sclerosis, 720 (53 %) were covered by the public drug insurance. Individuals with public drug coverage were younger, more likely to be materially and socially deprived, and had a lower median income than those with private insurance, but otherwise had similar sociodemographic characteristics. The proportion of people who had at least one multiple sclerosis-related visit to a general practitioner (39 % versus 45 %) and hospitalization (6 % versus 3 %) differed among those with public compared to private coverage. However, the utilization of other health services, including neurologist consultations, did not differ by type of drug coverage. Conclusion: People with multiple sclerosis covered by the public and private drug insurance differed in terms of age, income, deprivation, multiple sclerosis-related visits to a general practitioner and hospitalizations, but not neurologist consultations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score0.991

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.287
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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