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Record W4410027064 · doi:10.1371/journal.pone.0320843

Implementation and evaluation of the 3 Wishes Project in safety-net hospitals: Protocol for a hybrid effectiveness-implementation study

2025· article· en· W4410027064 on OpenAlexaff
Thanh H. Neville, Anne M. Walling, Neil S. Wenger, Brian S. Mittman, Chi‐Hong Tseng, Dong Chang, HOPE CASSANO, Emily Beers, RUCHA GADGIL, Nader Kamangar, Nancy Blake, Derjung M. Tarn

Bibliographic record

VenuePLoS ONE · 2025
Typearticle
Languageen
FieldMedicine
TopicPalliative Care and End-of-Life Issues
Canadian institutionsMcMaster University
FundersNational Institute of Nursing ResearchNational Institutes of HealthU.S. Department of Veterans Affairs
KeywordsBurnoutPsychological interventionMedicinePalliative careNursingIntervention (counseling)Protocol (science)AnxietyRandomized controlled trialHealth careFamily medicinePsychiatryClinical psychologyAlternative medicine

Abstract

fetched live from OpenAlex

BACKGROUND: Palliative care interventions in the intensive care unit have been shown to improve communication and the quality of death and dying. However, few interventions have been implemented in safety-net hospitals (SNHs), which provide healthcare to low income and uninsured patients. The 3 Wishes Project (3WP) is a low-cost intervention that aims to enhance compassionate end-of-life (EOL) experiences by empowering the clinical team to elicit and fulfill small wishes for patients who are dying in the ICU. OBJECTIVE: To implement and evaluate the 3WP in three SNHs in Los Angeles. METHODS: We conduct a pragmatic cluster-randomized stepped wedge type 2 hybrid effectiveness-implementation study to implement and evaluate the effect of the 3WP (compared to usual care) on quality of EOL ICU care, bereaved families' psychological symptoms, and clinician burnout. Prior to implementation, interviews with stakeholders from each hospital will refine the implementation strategy. Starting 6-10 months prior to 3WP implementation at each site and continuing throughout the study, we will survey bereaved families once 3 months after each patient's death. Surveys will query: EOL care, anxiety, depression, and post-traumatic stress disorder (PTSD). Each SNH ICU starts the 3WP at a randomly assigned time that is staggered by 2 months. Nurses are surveyed on burnout before implementation, 6 months, and 12 months after 3WP implementation. Semi-structured interviews are conducted with 10-12 family members per SNH who received 3WP and 10-12 nurses per SNH a year after implementation. We will use the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework to guide a mixed-methods evaluation of the 3WP implementation in SNHs. CONCLUSION: We hypothesize that it will be feasible to adapt and implement the 3WP in SNHs. We will evaluate how the 3WP improves EOL care in this setting and provide valuable insight regarding the adaptations necessary to tailor palliative care interventions for SNH ICUs. TRIAL REGISTRATION: ClinicalTrials.gov NCT06277310.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.108
metaresearch head score (Gemma)0.063
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.108
Threshold uncertainty score0.569

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1080.063
Meta-epidemiology (narrow)0.0060.004
Meta-epidemiology (broad)0.0060.005
Bibliometrics0.0040.004
Science and technology studies0.0050.005
Scholarly communication0.0040.005
Open science0.0050.004
Research integrity0.0070.009
Insufficient payload (model declined to judge)0.0530.011

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.250
GPT teacher head0.533
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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