Repeatability of artificial gravity tolerance times
Bibliographic record
Abstract
Introduction: Exposure to microgravity results in physiological deconditioning, including orthostatic intolerance. Artificial gravity (AG) from short-arm centrifuges is being tested in ground-based studies to counter these effects. Orthostatic tolerance testing with centrifuges before and after these spaceflight analogs could determine the efficacy of an AG countermeasure to orthostatic tolerance. However, there has not been an investigation on how long before analog testing AG orthostatic tolerance data would remain valid for such a study. Methods: A secondary analysis of two experiments involving AG orthostatic tolerance testing (starting at 0.6 for females and 0.8 Gz for males and increased by 0.1 Gz every 3 minutes until presyncope) conducted 7 months apart at MEDES revealed 4 male and 3 female participants who had taken part in both. Results: Comparisons of participants' time to presyncope between the two tests using Lin's concordance correlation coefficient (LCCC) showed a significant relationship in time to presyncope between the two test dates (LCCC = 0.98) for males but not for females (LCCC = -0.64). While the cardiovascular data from one female was unusable, the mean heart rate responses to increasing artificial gravity during the orthostatic tolerance procedure showed a strong linear correlation between the two tests for all other participants (all p < 0.008). The LCCC heart rate changes with centrifuge level varied across male participants from 0.61 to 0.97, suggesting that the high LCCC for time to presyncope was achieved with varied HR baselines between the two test dates. Discussion: These findings indicate that time-to-presyncope tests may remain valid up to 7 months after the testing date for males. We highly recommend further study with larger numbers of male and female participants.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".