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Record W4410075751 · doi:10.1038/s41598-025-98892-2

A new design to improve time resolution in a time of flight brain PET using dual layer offset scintillator crystals

2025· article· en· W4410075751 on OpenAlexafffundabout
Amir Beheshti, Alireza Karimian, Hossein Arabi, Andrew L. Goertzen

Bibliographic record

VenueScientific Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicMedical Imaging Techniques and Applications
Canadian institutionsUniversity of Manitoba
FundersUniversity of IsfahanUniversity of Manitoba
KeywordsScintillatorOffset (computer science)Dual layerTime of flightComputer scienceLayer (electronics)Resolution (logic)Dual (grammatical number)OpticsMaterials sciencePhysicsNanotechnologyDetectorArtificial intelligenceTelecommunications

Abstract

fetched live from OpenAlex

In PET systems, the SNR relies on the coincidence time resolution (CTR) of 511 keV photon pairs. This research investigates the impact of reflectors, surface treatments, materials, and scintillation crystal length on the CTR of a brainPET detector using dual-layer offset scintillators (DLOs). This study is based on a brainPET, under development at the University of Manitoba, to propose a new design to achieve an improved CTR. Four different pairs of LYSO crystals with distinct optical compositions, surface treatments, and reflective materials were simulated (using GATEv9.3). Each model comprises two LYSO crystal with dimensions of 3 × 3 × 10 mm 3 . Considering the initial experimental data from the brainPET lab, simulation results showed that the crystal with a roughened surface and ESR reflector demonstrated 13.6% energy resolution and an average 17.8% improvement in CTR compared to other models. In addition, a more comprehensive model, including a dual-layer offset detector was designed. The bottom and top layers have 25 × 19 and 24 × 18 crystals with thickness of 12 and 8 mm, respectively in the DLO model. The simulation investigation showed that the DLO configuration could enhance the time resolution by 17.5% and the energy resolution by 5.4% which are considerably comparable to the state-of-the-art brainPET systems.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.325
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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