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Record W4410078308 · doi:10.1093/nar/gkaf385

Heatmapper2: web-enabled heat mapping made easy

2025· article· en· W4410078308 on OpenAlexafffund
Kyle Kernick, Robyn Woudstra, Mark Berjanskii, Scott MacKay, David S. Wishart

Bibliographic record

VenueNucleic Acids Research · 2025
Typearticle
Languageen
FieldChemistry
Topicthermodynamics and calorimetric analyses
Canadian institutionsUniversity of Alberta
FundersGenome AlbertaCanada Foundation for InnovationGenome Canada
KeywordsPython (programming language)Geospatial analysisComputer scienceWeb applicationPersonalizationDatabaseUpgradeWorld Wide WebDistributed computingOperating systemCartography

Abstract

fetched live from OpenAlex

First released in 2016, Heatmapper provided the first comprehensive, web-based platform for easily visualizing and manipulating heat maps for a wide range of applications in biology, epidemiology, ecology, and many other areas of science and social science. However, as Heatmapper's popularity grew, limitations in its performance and functionality became more apparent, necessitating the development of a new version: Heatmapper2 (https://heatmapper2.ca/). Heatmapper2 represents a substantial upgrade to the original Heatmapper web server, with much of the code being completely rewritten to improve performance, enhance capabilities and integrate new web technologies. Among the key changes are the conversion of the back-end code from R to Python (for better processing speed), the migration away from R Shiny to Shiny Python, and the use of WebAssembly. WebAssembly enables high performance, graphically intense applications to be run client-side in a web browser. Moving computationally intense calculations away from a central server and on to client computers eliminates server congestion and significantly improves performance. In addition to its significantly improved performance, Heatmapper2 now supports a wider range of heat mapping options including: time-series or animated heat maps (for geospatial applications), 3D heat maps (for mapping data on organisms or body parts); protein structure heat maps (for mapping molecular dynamic processes), molecular spatial heat maps (for spatial omics applications), and spectrometric heat maps (for mass spectrometry applications). Heatmapper2's redesigned interface also supports much more extensive customization, more easily editable tables, and more efficient handling of large datasets. These enhancements should make Heatmapper2 much more appealing for a wider range of researchers and research applications.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.865
Threshold uncertainty score0.997

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.335
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2025
Admission routes2
Has abstractyes

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