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Record W4410095336 · doi:10.4314/rjmhs.v8i1.11

Marburg Virus Disease in Rwanda: The Role of Infection Prevention and Control in Reducing Transmission of Infectious Disease Outbreaks among Healthcare Professionals

2025· article· en· W4410095336 on OpenAlexaff
David Ryamukuru, Joselyne Mukantwari, Fauste Uwingabire, Gerard Nyiringango

Bibliographic record

VenueRwanda Journal of Medicine and Health Sciences · 2025
Typearticle
Languageen
FieldMedicine
TopicViral Infections and Outbreaks Research
Canadian institutionsWestern University
Fundersnot available
KeywordsOutbreakDiseaseTransmission (telecommunications)Marburg virusVirologyInfectious disease (medical specialty)Infection controlHealth professionalsHealth careMedicineDisease transmissionDisease controlIntensive care medicineEbola virusInternal medicinePolitical scienceComputer science

Abstract

fetched live from OpenAlex

Rwanda's first Marburg Virus Disease (MVD) outbreak resulted in 58 infections and 13 deaths within the first two weeks. Over 70% of cases occurred among healthcare professionals, highlighting the vulnerability of frontline workers and exposing critical gaps in the country's healthcare system, particularly in infection prevention and control (IPC) practices. Healthcare workers are essential to sustaining functional healthcare systems. However, they face a higher risk of infection and death at the onset of outbreaks, potentially due to lapses in IPC practices, thereby weakening the healthcare system. Routine and strict adherence to IPC measures would have protected healthcare workers and prevented the transmission of both known and emerging diseases. Thus far, Rwanda has successfully implemented containment strategies such as early detection, contact tracing, and isolation. However, this article argues that long-term investment in IPC protocols is essential to safeguard healthcare workers and ensure system resilience. Strengthening IPC measures and fostering a culture of safety are vital steps toward building a healthcare system capable of effectively managing future infectious disease outbreaks. This perspective article aims to raise awareness about the role of infection prevention and control in reducing the transmission of infectious disease outbreaks among healthcare professionals, motivated by the devastating consequences of the MVD outbreak on the health workforce in Rwanda.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.400
Teacher spread0.374 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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