MétaCan
Menu
Back to cohort
Record W4410105417 · doi:10.1093/ecco-jcc/jjaf079

Spatial mapping and geographic variation of inflammatory bowel disease in Canada: a population-based study

2025· article· en· W4410105417 on OpenAlexaffabout
Shane W. Goodwin, Michael Haan, Yuhong Yuan, Piotr Wilk, Vipul Jairath

Bibliographic record

VenueJournal of Crohn s and Colitis · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammatory Bowel Disease
Canadian institutionsWestern UniversityLawson Health Research Institute
Fundersnot available
KeywordsMedicineInflammatory bowel diseaseGeographic variationDemographyUlcerative colitisDiseaseDemographicsSpatial epidemiologyLocationPopulationEpidemiologyEnvironmental healthGeographyPathology

Abstract

fetched live from OpenAlex

BACKGROUND AND AIMS: Inflammatory bowel disease (IBD) poses significant challenges to healthcare systems, with rising prevalence globally. To address challenges of health resource allocation and understand the geographic distribution of disease in Canada, we explored spatial mapping of IBD across Canada. METHODS: Data from 2009 to 2018 Canadian Community Health Survey identified individuals with IBD. Crude and adjusted prevalence rates were calculated, and spatial dependencies were analyzed using Moran's I. Local indicators of spatial association identified hot-spots where the prevalence of IBD was significantly different than neighboring areas. Spatial autoregressive models assessed the influence of sociodemographic factors on spatial dependencies. RESULTS: Across 109 health regions, 492 560 individuals were included, representing 29 846 350 Canadians. Crohn's disease and ulcerative colitis were reported in 0.38% and 0.47% of Canadians, respectively. Age and sex-standardized prevalence ranged from 742 to 1267 per 100 000. Significant dependencies among health regions were found, but dependencies were explained by the distribution of sociodemographic characteristics in a region. CONCLUSIONS: Results demonstrated significant geographic variations in the prevalence of IBD in Canada. Evidence suggests that differences in prevalence between regions are primarily driven by individual demographics rather than geographical characteristics.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.020
Threshold uncertainty score0.144

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.007
Science and technology studies0.0030.001
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.207
Teacher spread0.203 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

Explore more

Same venueJournal of Crohn s and ColitisSame topicInflammatory Bowel DiseaseFrench-language works237,207