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Record W4410129348 · doi:10.1177/12034754251336238

Evaluating the Diagnostic and Treatment Capabilities of GPT-4 Vision in Dermatology: A Pilot Study

2025· article· en· W4410129348 on OpenAlexaff
Abhinav Pillai, Sharon Parappally-Joseph, Jason Kreutz, Danya Traboulsi, Maharshi Gandhi, Jori Hardin

Bibliographic record

VenueJournal of Cutaneous Medicine and Surgery · 2025
Typearticle
Languageen
FieldMedicine
TopicCutaneous Melanoma Detection and Management
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsMedicineWilcoxon signed-rank testMedical physicsArtificial intelligenceDiagnostic accuracyComputer scienceRadiologyInternal medicine

Abstract

fetched live from OpenAlex

Background: The integration of generative artificial intelligence within dermatology presents a new frontier for enhancing diagnostic accuracy and treatment planning. Objective: This research evaluates Generative Pre-trained Transformer-4 Vision’s (GPT-4V) performance in accurately diagnosing and generating treatment plans for common dermatological conditions, comparing its assessment of textual versus image data and its performance with multimodal inputs. Methods: A dataset of 102 images representing 9 common dermatological conditions was compiled from dermatlas.org and dermnet.nz . Images were screened by 2 board-certified dermatologists and were excluded if they did not represent a classic presentation of the respective conditions. Fifty-four images were included in the final analysis. In addition, 9 text-based clinical scenarios corresponding to each condition were developed. GPT-4V’s diagnostic capabilities were assessed across 3 setups: Image Prompt, Scenario Prompt, and Image + Scenario Prompt. Results: In the Image Prompt setup, GPT-4V correctly identified the primary diagnosis for 54% of the images. The Scenario Prompt and the Image + Scenario Prompt setups, respectively, both achieved an 89% accuracy rate in identifying the primary diagnosis. Treatment recommendations were evaluated using a modified Entrustment Scale, showing competent but not expert-level performance. A Wilcoxon signed-rank test demonstrated a statistically significant difference in treatment recommendations based on the Entrustment Score, with the model performing better in the Image + Scenario setup ( P < .01). Conclusion: GPT-4V demonstrates the potential to augment dermatological diagnosis and treatment recommendations, particularly in text-based scenarios. However, its underwhelming performance in image-based diagnosis and integration of multimodal data highlights important areas for improvement.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.009
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.009
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.357
Teacher spread0.302 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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