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Record W4410133002 · doi:10.1101/2025.05.05.652210

A network of face patches in human prefrontal cortex for social processing of faces

2025· preprint· en· W4410133002 on OpenAlexaff
Asa Farahani, Mojan Izadkhah, Roza Hamidi, Elahe’ Yargholi, Gholam‐Ali Hossein‐Zadeh, Reza Rajimehr

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldNeuroscience
TopicFace Recognition and Perception
Canadian institutionsUniversity of British ColumbiaMcGill UniversityMontreal Neurological Institute and Hospital
Fundersnot available
KeywordsPrefrontal cortexFace (sociological concept)Cognitive psychologyPsychologyNeuroscienceComputer scienceCognitive scienceCognitionSociology

Abstract

fetched live from OpenAlex

ABSTRACT The human cerebral cortex contains localized regions for processing faces. These regions or patches, which are classically found in the occipito-temporal cortex, encode visual properties of faces. Using naturalistic movie-watching fMRI data from 176 human subjects and multivariate functional connectivity analysis, here we comprehensively characterize a novel network of four frontal face patches (FFPs) arranged dorsoventrally in the lateral prefrontal cortex. FFPs are strongly coupled with a face-selective region in the middle superior temporal sulcus, appear to be primarily involved in processing high-level social aspects of faces during movie-watching, and show partial correlations of activity with distinct cognitive networks. Activations in FFPs are correlated with the performance of subjects in a social cognition task. We further identify two groups of subjects who showed a remarkable difference in the topographical organization of FFPs. The discovery of FFPs provides new insights into the understanding of social processing in the brain.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.287
Teacher spread0.239 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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