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Record W4410178229 · doi:10.32942/x27p8q

Predicting high pathogenicity avian influenza H5N1 susceptibility in wild birds, with special reference to Australia

2025· preprint· en· W4410178229 on OpenAlexfundno aff
Sara Ryding, Tobias L. Roß, Marcel Klaassen

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldMedicine
TopicInfluenza Virus Research Studies
Canadian institutionsnot available
FundersInstitute of Infection and Immunity
KeywordsInfluenza A virus subtype H5N1PathogenicityBiologyHighly pathogenicZoologyVirologyGeographyVeterinary medicineMicrobiologyMedicineVirus

Abstract

fetched live from OpenAlex

High pathogenicity avian influenza (HPAI) has caused widespread sickness and mortality in poultry and wildlife, especially since the emergence of a novel H5 virus belonging to clade 2.3.4.4b in 2021. The ongoing panzootic caused by this lineage has infected an unprecedented diversity of species across the globe. Here, we analyse outbreak notifications of HPAI in wild birds to understand the impacts of species’ ecologies and phylogeny on HPAI notifications and predict host susceptibility to HPAI H5N1 for Australia, as the only continent thus far unaffected by this virus. We found a significant family-level phylogenetic signal in HPAI notifications in wild birds. Furthermore, we found that adding ecological traits to this phylogenetic information does not improve explanatory power of HPAI notifications. Using the family-level phylogenies to predict HPAI H5N1 susceptibility in Australian birds, we predict that families of Australian seabirds, shorebirds, and waterbirds will be most susceptible to HPAI H5N1 once it arrives on the continent. Our results provide an empirical indication of species susceptible to HPAI H5N1, with special reference to Australia, which can be used in conjunction with conservation status and other species-specific information to inform preparedness activities, monitoring, and response upon incursion.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.020
Threshold uncertainty score0.039

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.137
GPT teacher head0.407
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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