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Record W4410197753 · doi:10.1016/j.idairyj.2025.106291

Application of multivariate adaptive regression splines (MARS) to study the colorization occurring in the process of lactulose production following lactose electro-activation

2025· article· en· W4410197753 on OpenAlexafffund
Abdullah Nayeem, Hossein Bonakdari, Seddik Khalloufi, Mohammed Aïder

Bibliographic record

VenueInternational Dairy Journal · 2025
Typearticle
Languageen
FieldChemistry
TopicSpectroscopy and Chemometric Analyses
Canadian institutionsUniversity of OttawaUniversité LavalAgriculture and Agri-Food Canada
FundersFonds de recherche du Québec – Nature et technologies
KeywordsLactuloseMultivariate adaptive regression splinesLactoseMultivariate statisticsMars Exploration ProgramProcess (computing)RegressionBayesian multivariate linear regressionRegression analysisEnvironmental scienceComputer scienceStatisticsChemistryFood scienceMathematicsBiologyBiochemistry

Abstract

fetched live from OpenAlex

Lactulose is widely used in the food and pharmaceutical industries and is obtained from the chemical and enzymatic isomerization processes of lactose. Recently, electro-activation, a chemical-free process, has been effectively used for lactulose production at ambient temperature. However, the electro-activated (EA) isomerization process produces colored lactose solutions like the conventional chemical isomerization processes, which becomes a concerning issue. In this context, artificial intelligence-based machine learning tools can be pivotal. The current study observed the color development due to the EA isomerization process and established a model using the multivariate adaptive regression spline (MARS). The color development was expressed in terms of total color difference (ΔE ab ) using the seven input parameters, such as reaction type, reaction time, relaxation time, relaxation temperature, L* , a* , and b* . A total of 127 configurations resulting from the combination of input numbers (1-7) were employed to understand the color development using MARS. The K-fold (K=10) cross-validation technique was applied to select the best-fit combination for each input configuration that underscored the non-linear and complex nature of the color development, offering insights about the input parameters. The reaction type, reaction time, a *, and b* were identified as the key parameters of the color development. The corresponding basis functions of the best-fit configurations reflected the interactions and connected the nonlinearities across the input parameters to understand their impact on the color development using the MARS algorithm.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.128
Threshold uncertainty score0.286

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.355
Teacher spread0.338 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes2
Has abstractyes

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