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Record W4410248033 · doi:10.3389/fcell.2025.1602463

Establishing cell polarity in plants: the role of cytoskeletal structures and regulatory pathways

2025· review· en· W4410248033 on OpenAlexaff
Chao Ma, Jianbin Chang, Olivia S Hazelwood, M. Arif Ashraf, Qiong Nan

Bibliographic record

VenueFrontiers in Cell and Developmental Biology · 2025
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPlant Reproductive Biology
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsCell polarityCytoskeletonCell biologyBiologyMicrotubuleActin cytoskeletonActinArabidopsisTip growthPolarity (international relations)Root hairActin remodelingPollen tubeCellBotanyPollenBiochemistry

Abstract

fetched live from OpenAlex

Cell polarity is a fundamental mechanism of plant cells that drives cellular specialization and the formation of diverse cell types. It regulates critical developmental events, including polarized tip growth (such as pollen tubes and root hairs), epidermal patterning (such as trichome branching and asymmetric cell division in stomata). The establishment and maintenance of cell polarity rely on the cytoskeleton-mediated polarized distribution of specific proteins and organelles. In particular, cell-type-specific actin and microtubule dynamic structures are pivotal for maintaining polarity. For example, actin cables and short actin fragments are critical for pollen tube growth, while actin clusters and microtubule rings are involved in trichome branching, and actin patches contribute to stomatal mother cell polarization. Beyond directing the polarization of organelles and proteins, the cytoskeleton itself serves as an intrinsic cue for polarity. For instance, actin patches in stomatal precursor cells act as self-organizing polarity landmarks. Despite the diversity of cytoskeletal structures and their functions, common regulators, such as Rop GTPase signaling pathways, WAVE/SCAR complexes, and motor proteins regulate the assembly and function of these structures. Recent advances have revealed new regulatory mechanisms, such as microtubule exclusion zones guiding asymmetric divisions during Arabidopsis stomatal development, and the role of actin rings in regulating xylem pit formation. These discoveries contribute to a deeper understanding of the cytoskeleton's crucial role in polarity regulation. In this review, we highlight the key cytoskeletal structures involved in the establishment of cell polarity in plants and discuss the molecular mechanisms underlying their spatiotemporal assembly. We also address emerging questions regarding the cytoskeleton's role in cell polarity and development.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.977
Threshold uncertainty score0.985

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.222
Teacher spread0.214 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes1
Has abstractyes

Explore more

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