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Record W4410258887 · doi:10.56294/shp2025208

Calcium Role In The Treatment Of Hemorrhagic Shock

2025· article· en· W4410258887 on OpenAlexaboutno aff
Louise Amoedo Do Amor Divino, Adolfo Savia

Bibliographic record

VenueSouth Health and Policy · 2025
Typearticle
Languageen
FieldMedicine
TopicTrauma, Hemostasis, Coagulopathy, Resuscitation
Canadian institutionsnot available
Fundersnot available
KeywordsHemorrhagic shockCalciumShock (circulatory)MedicineInternal medicine

Abstract

fetched live from OpenAlex

Hemorrhagic Shock is a type of Hypovolemic Shock caused by large blood loss, making tissue perfusion difficult. Advanced Trauma Life Support (ATLS) emphasizes the need for a systematic and organized approach to the management of hemorrhagic shock, prioritizing rapid control of hemorrhage and restoration of adequate tissue perfusion through aggressive and timely resuscitation. Due to its effects on coagulation, cardiac function and nerve conduction, in recent years there has been a need to monitor and eventually administer calcium supplements to patients with Hemorrhagic Shock as part of a package of measures to improve hemostasis. Citrate used as an anticoagulant in blood products during massive transfusions can result in the reduction of ionized calcium, with negative results on hemostasis as well as other physiological processes in which calcium is central. To improve clinical results in these patients, proactive monitoring and correction of calcium levels, a situation that occurs more and more frequently and is evident in a number of recent publications on the matter. Objective: To deepen the understanding of how calcium regulation can influence the clinical evolution and therapeutic management of patients with hemorrhagic shock, based on available scientific publications. Material and Methods: To collect data, a search was carried out in digital databases such as PUBMED, SCIELO (Scientific Electronic Library Online). The articles were downloaded from these platforms and the Vancouver system was used to manage appropriate citations and references. The study is based on latest literature that highlights the importance of monitoring calcium levels and its adequate replacement to prevent complications associated with hypocalcemia during the treatment of hemorrhagic shock, in order to ament clinical outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.006
Threshold uncertainty score0.020

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0040.004
Science and technology studies0.0000.000
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.368
Teacher spread0.335 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueSouth Health and Policy→Same topicTrauma, Hemostasis, Coagulopathy, Resuscitation→French-language works237,207→