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Record W4410259827 · doi:10.7759/cureus.83828

Secondary Cicatricial Scalp Alopecia Caused by Brunsting-Perry Pemphigoid: A Case Report

2025· article· en· W4410259827 on OpenAlexaff
Ihor Kohut, Antonina Kalmykova, Halyna Bezkorovayna

Bibliographic record

VenueCureus · 2025
Typearticle
Languageen
FieldMedicine
TopicAutoimmune Bullous Skin Diseases
Canadian institutionsSKiN Health
Fundersnot available
KeywordsMedicineScalpDermatologyCicatricial pemphigoidPemphigoidBullous pemphigoid

Abstract

fetched live from OpenAlex

Brunsting-Perry pemphigoid is a rare, chronically persistent bullous dermatosis, localized to the head, scalp, and neck, causing residual scars and cicatricial alopecia. Herein, we present a case of Brunsting-Perry pemphigoid in a 68-year-old Caucasian woman presenting with over 10 years of history of slowly progressing patchy cicatricial alopecia. Dermoscopy showed scarring, a milky red background, and a typical picture of a "fried-egg sign" representing specific follicular damage. A skin biopsy revealed a subepidermal blister with dermal inflammation. Immunopathology shows strong linear continuous deposits of C3c and IgM along the basement membrane, and moderate to weak linear reactions to IgG and IgA. Intralesional betamethasone was successful in the treatment, and topical mometasone furoate lotion was used to maintain the result. Our case suggests that Brunsting-Perry pemphigoid may be underdiagnosed as the reason for scarring alopecia, considering the scarce information about the disease in the literature.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.135
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.286
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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