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Record W4410264376 · doi:10.1016/j.ejcped.2025.100240

Impact of COVID-19 pandemic on childhood cancer incidence and stage in France – A national registry-based study

2025· article· en· W4410264376 on OpenAlexaboutno aff
Maud Gédor, Brigitte Lacour, Sandra Guissou, Laure Faure, Claire Poulalhon, François Doz, Arnaud Petit, Jérémie Rouger, Virginie Gandemer, Emmanuel Désandes, Jacqueline Clavel

Bibliographic record

VenueEJC Paediatric Oncology · 2025
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 and healthcare impacts
Canadian institutionsnot available
FundersInstitut National Du CancerInstitut National de la Santé et de la Recherche MédicaleSociété Française de lutte contre les Cancers et les leucémies de l'Enfant et de l'Adolescent
KeywordsCoronavirus disease 2019 (COVID-19)PandemicCancer registryIncidence (geometry)2019-20 coronavirus outbreakChildhood cancerStage (stratigraphy)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MedicineDemographyCancerVirologySociologyPathologyOutbreakInternal medicineDisease

Abstract

fetched live from OpenAlex

COVID-19 pandemic has considerably affected access to healthcare ressources with global decline in cancer care activities in 2020. This national study aimed to assess a possible impact of the pandemic on the management of pediatric cancer cases. Methods The study was based on the French National Childhood Cancer Registry and included all cases of cancer under 18 years of age diagnosed between January 1, 2016 and December 31, 2020. We estimated incidence rates, the proportion of advanced/metastatic stages (Toronto Pediatric Cancer Stage Guidelines) and the distribution of treatment initiation time during the 2020 pandemic period compared to the 2016-2019 reference period. Results Age-standardized incidence rates of overall pediatric cancer were similar in 2020 (161.4 cases per million person-years; 2,250 cases) and in 2016–2019 (162.4 cases per million person-years; 9,208 cases). They were also similar by sex, age group, region, and cancer type. We did not observe any significant differences in stage at diagnosis or median time to treatment. Conclusion Our nationwide population-based study suggests that pediatric cancer management was not substantially altered in 2020, despite the challenges induced by the COVID-19 pandemic and associated lockdown.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.016
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.054
GPT teacher head0.477
Teacher spread0.424 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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