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Record W4410293183 · doi:10.2196/60125

Peer Relationships Are a Direct Cause of the Adolescent Mental Health Crisis: Interpretable Machine Learning Analysis of 2 Large Cohort Studies

2025· article· en· W4410293183 on OpenAlexvenueno aff
Heiner Stuke, Robert Schlack, Michael Erhart, Anne Kaman, Ulrike Ravens‐Sieberer, Christopher Irrgang

Bibliographic record

VenueJMIR Public Health and Surveillance · 2025
Typearticle
Languageen
FieldPsychology
TopicMental Health Research Topics
Canadian institutionsnot available
Fundersnot available
KeywordsMental healthCohortPsychologyCausal inferenceCohort studyMedicinePsychiatryClinical psychologyGerontologyDemography

Abstract

fetched live from OpenAlex

Background: Converging evidence indicates an adolescent mental health crisis in Western societies that has developed and exacerbated over the past decade. The proposed driving factors of this trend include more screen time, physical inactivity, and social isolation, but their causal influence on mental health is insufficiently understood. Objective: The objective of this study is to test whether and based on which predictor variables the development of mental health in adolescents in the last decade can be predicted and to better understand the causal chain of factors at work. Methods: We implemented an interpretable machine learning pipeline based on gradient boosting regression with repeated cross-validation to assess the development of mental health throughout adolescence in members of 2 longitudinal cohort studies, the British Millenium cohort (MC; n=8599) and the German Health Interview and Examination Survey for Children and Adolescents (KiGGS) cohort (n=1212). In total, 144 (MC) and 102 (KiGGS) predictors assessed at the age of around 13.8 years (MC) and 11.6 years (KiGGS) were used to assess mental health at the ages of around 16.7 years (MC) and 16.4 years (KiGGS). Based on these predictive models, we used permutation-based feature importance analyses to identify relevant predictors and predictor domains. Moreover, we performed partial dependence analyses in a causal inference framework to determine the direct effects of physical inactivity, screen time, and peer problems on the development of mental health. Results: The average cross-validated Pearson correlation coefficient (r) between predicted and true mental health in late adolescence was 0.614 (MC) and 0.466 (KiGGS). Feature importance analyses indicated a strong impact of preexisting mental health and weaker impacts of sex (female as a risk factor), physical health (chronic disease as a risk factor), lifestyle, and socioeconomic and family factors (eg, low parental education, income, and mental health as risk factors). Causal inference analyses suggested a strong direct effect of peer relationships, but only a small direct effect of physical inactivity and a very small direct effect of screen time. Conclusions: Mental health development during adolescence can be assessed by a combination of variables from early adolescence. Peer problems represent an important direct cause of mental health development, and their deterioration may contribute to the current mental health crisis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.054
metaresearch head score (Gemma)0.072
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.054
Threshold uncertainty score0.288

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0540.072
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.004
Bibliometrics0.0020.002
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0020.003
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.094
GPT teacher head0.449
Teacher spread0.355 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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